2BTP
14-3-3 Protein Theta (Human) Complexed to Peptide
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0005925 | cellular_component | focal adhesion |
| A | 0007165 | biological_process | signal transduction |
| A | 0008104 | biological_process | intracellular protein localization |
| A | 0016020 | cellular_component | membrane |
| A | 0019904 | molecular_function | protein domain specific binding |
| A | 0021762 | biological_process | substantia nigra development |
| A | 0032991 | cellular_component | protein-containing complex |
| A | 0034766 | biological_process | negative regulation of monoatomic ion transmembrane transport |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0044325 | molecular_function | transmembrane transporter binding |
| A | 0045202 | cellular_component | synapse |
| A | 0045892 | biological_process | negative regulation of DNA-templated transcription |
| A | 0070062 | cellular_component | extracellular exosome |
| A | 0071889 | molecular_function | 14-3-3 protein binding |
| B | 0005515 | molecular_function | protein binding |
| B | 0005634 | cellular_component | nucleus |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0005925 | cellular_component | focal adhesion |
| B | 0007165 | biological_process | signal transduction |
| B | 0008104 | biological_process | intracellular protein localization |
| B | 0016020 | cellular_component | membrane |
| B | 0019904 | molecular_function | protein domain specific binding |
| B | 0021762 | biological_process | substantia nigra development |
| B | 0032991 | cellular_component | protein-containing complex |
| B | 0034766 | biological_process | negative regulation of monoatomic ion transmembrane transport |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0044325 | molecular_function | transmembrane transporter binding |
| B | 0045202 | cellular_component | synapse |
| B | 0045892 | biological_process | negative regulation of DNA-templated transcription |
| B | 0070062 | cellular_component | extracellular exosome |
| B | 0071889 | molecular_function | 14-3-3 protein binding |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Site: {"description":"Interaction with phosphoserine on interacting protein"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N-acetylmethionine","evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"FEB-2008","submissionDatabase":"UniProtKB","authors":["Bienvenut W.V.","Dhillon A.S.","Kolch W."]}},{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"25944712","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N6-acetyllysine; alternate","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"3'-nitrotyrosine","evidences":[{"source":"UniProtKB","id":"Q9CQV8","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P68254","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 4 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
