Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0005200 | molecular_function | structural constituent of cytoskeleton |
| A | 0005515 | molecular_function | protein binding |
| A | 0005525 | molecular_function | GTP binding |
| A | 0005874 | cellular_component | microtubule |
| A | 0007010 | biological_process | cytoskeleton organization |
| A | 0007017 | biological_process | microtubule-based process |
| A | 0016787 | molecular_function | hydrolase activity |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0005200 | molecular_function | structural constituent of cytoskeleton |
| B | 0005515 | molecular_function | protein binding |
| B | 0005525 | molecular_function | GTP binding |
| B | 0005874 | cellular_component | microtubule |
| B | 0007010 | biological_process | cytoskeleton organization |
| B | 0007017 | biological_process | microtubule-based process |
| B | 0016787 | molecular_function | hydrolase activity |
| T | 0005515 | molecular_function | protein binding |
| T | 0005737 | cellular_component | cytoplasm |
| T | 0005829 | cellular_component | cytosol |
| T | 0015035 | molecular_function | protein-disulfide reductase activity |
| T | 0015036 | molecular_function | disulfide oxidoreductase activity |
| T | 0030337 | molecular_function | DNA polymerase processivity factor activity |
| T | 0045454 | biological_process | cell redox homeostasis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR RESIDUE GTP A1433 |
| Chain | Residue |
| A | GLY12 |
| A | THR147 |
| A | GLY148 |
| A | VAL173 |
| A | PRO175 |
| A | GLU185 |
| A | ASN208 |
| A | VAL226 |
| A | ASN230 |
| A | ILE233 |
| A | HOH2102 |
| A | GLN13 |
| A | HOH2103 |
| A | HOH2104 |
| A | HOH2105 |
| A | HOH2106 |
| A | HOH2107 |
| A | HOH2108 |
| T | ARG92 |
| A | ALA14 |
| A | GLN17 |
| A | ALA101 |
| A | GLY103 |
| A | ALA142 |
| A | GLY145 |
| A | GLY146 |
| site_id | AC2 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE GTP B1433 |
| Chain | Residue |
| B | GLY12 |
| B | GLN13 |
| B | ALA14 |
| B | GLN17 |
| B | GLY100 |
| B | ALA101 |
| B | GLY103 |
| B | ALA142 |
| B | GLY145 |
| B | GLY146 |
| B | THR147 |
| B | GLY148 |
| B | PRO175 |
| B | GLU185 |
| B | ASN208 |
| B | VAL226 |
| B | ASN230 |
| B | HOH2039 |
Functional Information from PROSITE/UniProt
| site_id | PS00194 |
| Number of Residues | 19 |
| Details | THIOREDOXIN_1 Thioredoxin family active site. LVdFWaeWCGPCKmIapiL |
| Chain | Residue | Details |
| T | LEU43-LEU61 | |
| site_id | PS00227 |
| Number of Residues | 7 |
| Details | TUBULIN Tubulin subunits alpha, beta, and gamma signature. GGGTGSG |
| Chain | Residue | Details |
| A | GLY144-GLY150 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Nucleophile |
| Chain | Residue | Details |
| T | GLY52 | |
| T | LYS55 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | SITE: Deprotonates C-terminal active site Cys |
| Chain | Residue | Details |
| T | PHE46 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | SITE: Contributes to redox potential value |
| Chain | Residue | Details |
| T | PRO53 | |
| T | CYS54 | |
| Chain | Residue | Details |
| T | TYR89 | |
