Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005507 | molecular_function | copper ion binding |
| A | 0008131 | molecular_function | primary amine oxidase activity |
| A | 0009308 | biological_process | amine metabolic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0048038 | molecular_function | quinone binding |
| A | 0052595 | molecular_function | aliphatic amine oxidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CU A1629 |
| Chain | Residue |
| A | HIS431 |
| A | HIS433 |
| A | HIS592 |
| A | HOH2290 |
| A | HOH2328 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA A1630 |
| Chain | Residue |
| A | HOH2334 |
| A | ASP440 |
| A | MET441 |
| A | ASP581 |
| A | ILE582 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE SO4 A1632 |
| Chain | Residue |
| A | ASP316 |
| A | CYS317 |
| A | LEU318 |
| A | HIS345 |
| A | GLY350 |
| A | ARG367 |
| A | GOL1639 |
| A | HOH2292 |
| A | HOH2293 |
| A | HOH2496 |
| A | HOH2497 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A1633 |
| Chain | Residue |
| A | THR233 |
| A | GLY234 |
| A | HOH2498 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A1634 |
| Chain | Residue |
| A | ARG545 |
| A | HOH2456 |
| A | HOH2499 |
| site_id | AC6 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE R4A A1631 |
| Chain | Residue |
| A | GLU102 |
| A | PHE105 |
| A | ALA135 |
| A | PRO136 |
| A | LEU137 |
| A | TRP168 |
| A | TYR296 |
| A | TYR302 |
| A | GLN306 |
| A | TYR307 |
| A | ASN309 |
| A | ARG336 |
| A | SER356 |
| A | ASP357 |
| A | LEU358 |
| A | THR378 |
| A | ILE379 |
| A | GLY380 |
| A | ASN381 |
| A | TPQ382 |
| A | HOH2289 |
| site_id | AC7 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL A1635 |
| Chain | Residue |
| A | ARG532 |
| A | ARG533 |
| A | THR554 |
| A | PHE557 |
| A | HIS561 |
| A | SER562 |
| A | GLY563 |
| A | GLY564 |
| A | ALA565 |
| A | HOH2436 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A1636 |
| Chain | Residue |
| A | ASN126 |
| A | ASP161 |
| A | VAL197 |
| A | ALA199 |
| A | HOH2500 |
| A | HOH2501 |
| A | HOH2502 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL A1637 |
| Chain | Residue |
| A | ASP605 |
| A | LYS610 |
| A | HOH2468 |
| site_id | BC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A1638 |
| Chain | Residue |
| A | LEU209 |
| A | THR210 |
| A | SER620 |
| A | PRO621 |
| A | VAL622 |
| A | LEU623 |
| A | ASP624 |
| A | HOH2504 |
| site_id | BC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE GOL A1639 |
| Chain | Residue |
| A | GLU347 |
| A | TRP349 |
| A | ARG370 |
| A | LYS401 |
| A | SO41632 |
| A | HOH2265 |
| A | HOH2267 |
| A | HOH2303 |
| A | HOH2497 |
| A | HOH2505 |
| A | HOH2506 |
| site_id | BC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A1640 |
| Chain | Residue |
| A | ASN368 |
| A | ASP393 |
| A | LYS610 |
| A | HOH2287 |
| A | HOH2476 |
| A | HOH2479 |
| A | HOH2507 |
| A | HOH2508 |
Functional Information from PROSITE/UniProt
| site_id | PS01164 |
| Number of Residues | 14 |
| Details | COPPER_AMINE_OXID_1 Copper amine oxidase topaquinone signature. MVIsfftTigNYDY |
| Chain | Residue | Details |
| A | MET371-TYR384 | |
| site_id | PS01165 |
| Number of Residues | 14 |
| Details | COPPER_AMINE_OXID_2 Copper amine oxidase copper-binding site signature. TfGltHFprvEDwP |
| Chain | Residue | Details |
| A | THR587-PRO600 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP298 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | ACT_SITE: Schiff-base intermediate with substrate; via topaquinone => ECO:0000250|UniProtKB:P12807 |
| Chain | Residue | Details |
| A | TPQ382 | |
| Chain | Residue | Details |
| A | TYR296 | |
| Chain | Residue | Details |
| A | ILE379 | |
| site_id | SWS_FT_FI5 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:9405045, ECO:0007744|PDB:1AV4, ECO:0007744|PDB:1AVL, ECO:0007744|PDB:1IU7, ECO:0007744|PDB:1IVU, ECO:0007744|PDB:1IVV, ECO:0007744|PDB:1IVW, ECO:0007744|PDB:1IVX, ECO:0007744|PDB:1RJO, ECO:0007744|PDB:1SIH, ECO:0007744|PDB:1SII, ECO:0007744|PDB:1UI8, ECO:0007744|PDB:1W4N, ECO:0007744|PDB:1W5Z, ECO:0007744|PDB:1W6C, ECO:0007744|PDB:1W6G, ECO:0007744|PDB:2BT3, ECO:0007744|PDB:2CFD, ECO:0007744|PDB:2CFG, ECO:0007744|PDB:2CFK, ECO:0007744|PDB:2CFL, ECO:0007744|PDB:2CFW, ECO:0007744|PDB:2CG0, ECO:0007744|PDB:2CG1, ECO:0007744|PDB:2CWT, ECO:0007744|PDB:2CWU, ECO:0007744|PDB:2CWV, ECO:0007744|PDB:2D1W, ECO:0007744|PDB:2E2T, ECO:0007744|PDB:2E2U, ECO:0007744|PDB:2E2V, ECO:0007744|PDB:2YX9, ECO:0007744|PDB:2ZL8, ECO:0007744|PDB:3AMO, ECO:0007744|PDB:3KII, ECO:0007744|PDB:3KN4, ECO:0007744|PDB:3WA2, ECO:0007744|PDB:3WA3 |
| Chain | Residue | Details |
| A | HIS431 | |
| A | HIS433 | |
| A | HIS592 | |
| Chain | Residue | Details |
| A | TPQ382 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1oac |
| Chain | Residue | Details |
| A | ASP298 | |
