2BRU
Complex of the domain I and domain III of Escherichia coli transhydrogenase
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE NAD B 1 |
| Chain | Residue |
| B | ARG1120 |
| B | ARG1197 |
| B | GLU1238 |
| B | ALA1256 |
| B | LEU1257 |
| B | VAL1375 |
| C | VAL71 |
| C | MET133 |
| C | NAP1001 |
| B | SER1122 |
| B | GLN1125 |
| B | GLY1172 |
| B | GLY1174 |
| B | VAL1175 |
| B | PHE1194 |
| B | ASP1195 |
| B | THR1196 |
| site_id | AC2 |
| Number of Residues | 31 |
| Details | BINDING SITE FOR RESIDUE NAP C1001 |
| Chain | Residue |
| B | NAD1 |
| B | GLN1203 |
| C | GLY38 |
| C | TYR39 |
| C | GLY40 |
| C | VAL43 |
| C | ALA44 |
| C | PRO70 |
| C | VAL71 |
| C | ALA72 |
| C | GLY73 |
| C | ARG74 |
| C | LEU75 |
| C | PRO76 |
| C | GLY113 |
| C | ALA114 |
| C | ASN115 |
| C | ASP116 |
| C | THR117 |
| C | ILE130 |
| C | MET133 |
| C | PHE147 |
| C | LYS148 |
| C | ARG149 |
| C | SER150 |
| C | ASN152 |
| C | GLY154 |
| C | TYR155 |
| C | GLY173 |
| C | ASP174 |
| C | ALA175 |
Functional Information from PROSITE/UniProt
| site_id | PS00430 |
| Number of Residues | 114 |
| Details | TONB_DEPENDENT_REC_1 TonB-dependent receptor (TBDR) proteins signature 1. mhhhhhhssqevgehreitaeetaellknshsviitpgygmavaqaqypvaeiteklrarginvrfgihpvagrlpghmnvllaeakvpydivlemdeinddfadt.........DTVLVIGA |
| Chain | Residue | Details |
| C | MET1-ALA114 |
| site_id | PS00836 |
| Number of Residues | 27 |
| Details | ALADH_PNT_1 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 1. GIPrErltNEt..RVAaTPkTVeqLlKlG |
| Chain | Residue | Details |
| A | GLY1004-GLY1030 |
| site_id | PS00837 |
| Number of Residues | 26 |
| Details | ALADH_PNT_2 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. VIGAGvAGlaAigaAnSLGAiVrafD |
| Chain | Residue | Details |
| A | VAL1170-ASP1195 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 14 |
| Details | Binding site: {"evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"MAY-2005","submissionDatabase":"PDB data bank","title":"Structure determination of a transient complex by NMR using paramagnetic distance restraints - the complex of the soluble domains of Escherichia coli transhydrogenase.","authors":["Johansson T.","Pedersen A.","Leckner J.","Karlsson B.G."]}}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 20 |
| Details | Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 132 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1djl |
| Chain | Residue | Details |
| C | TYR155 | |
| C | ARG74 | |
| C | TYR39 |
