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2BR7

Crystal Structure of Acetylcholine-binding Protein (AChBP) from Aplysia californica in complex with HEPES

Functional Information from GO Data
ChainGOidnamespacecontents
A0004888molecular_functiontransmembrane signaling receptor activity
A0005216molecular_functionmonoatomic ion channel activity
A0005230molecular_functionextracellular ligand-gated monoatomic ion channel activity
A0005515molecular_functionprotein binding
A0006811biological_processmonoatomic ion transport
A0007165biological_processsignal transduction
A0007271biological_processsynaptic transmission, cholinergic
A0015464molecular_functionacetylcholine receptor activity
A0016020cellular_componentmembrane
A0022848molecular_functionacetylcholine-gated monoatomic cation-selective channel activity
A0034220biological_processmonoatomic ion transmembrane transport
A0035094biological_processresponse to nicotine
A0042391biological_processregulation of membrane potential
A0042802molecular_functionidentical protein binding
A0043005cellular_componentneuron projection
A0045202cellular_componentsynapse
A0046872molecular_functionmetal ion binding
A0050877biological_processnervous system process
A0060078biological_processregulation of postsynaptic membrane potential
A0060079biological_processexcitatory postsynaptic potential
A0098794cellular_componentpostsynapse
B0004888molecular_functiontransmembrane signaling receptor activity
B0005216molecular_functionmonoatomic ion channel activity
B0005230molecular_functionextracellular ligand-gated monoatomic ion channel activity
B0005515molecular_functionprotein binding
B0006811biological_processmonoatomic ion transport
B0007165biological_processsignal transduction
B0007271biological_processsynaptic transmission, cholinergic
B0015464molecular_functionacetylcholine receptor activity
B0016020cellular_componentmembrane
B0022848molecular_functionacetylcholine-gated monoatomic cation-selective channel activity
B0034220biological_processmonoatomic ion transmembrane transport
B0035094biological_processresponse to nicotine
B0042391biological_processregulation of membrane potential
B0042802molecular_functionidentical protein binding
B0043005cellular_componentneuron projection
B0045202cellular_componentsynapse
B0046872molecular_functionmetal ion binding
B0050877biological_processnervous system process
B0060078biological_processregulation of postsynaptic membrane potential
B0060079biological_processexcitatory postsynaptic potential
B0098794cellular_componentpostsynapse
C0004888molecular_functiontransmembrane signaling receptor activity
C0005216molecular_functionmonoatomic ion channel activity
C0005230molecular_functionextracellular ligand-gated monoatomic ion channel activity
C0005515molecular_functionprotein binding
C0006811biological_processmonoatomic ion transport
C0007165biological_processsignal transduction
C0007271biological_processsynaptic transmission, cholinergic
C0015464molecular_functionacetylcholine receptor activity
C0016020cellular_componentmembrane
C0022848molecular_functionacetylcholine-gated monoatomic cation-selective channel activity
C0034220biological_processmonoatomic ion transmembrane transport
C0035094biological_processresponse to nicotine
C0042391biological_processregulation of membrane potential
C0042802molecular_functionidentical protein binding
C0043005cellular_componentneuron projection
C0045202cellular_componentsynapse
C0046872molecular_functionmetal ion binding
C0050877biological_processnervous system process
C0060078biological_processregulation of postsynaptic membrane potential
C0060079biological_processexcitatory postsynaptic potential
C0098794cellular_componentpostsynapse
D0004888molecular_functiontransmembrane signaling receptor activity
D0005216molecular_functionmonoatomic ion channel activity
D0005230molecular_functionextracellular ligand-gated monoatomic ion channel activity
D0005515molecular_functionprotein binding
D0006811biological_processmonoatomic ion transport
D0007165biological_processsignal transduction
D0007271biological_processsynaptic transmission, cholinergic
D0015464molecular_functionacetylcholine receptor activity
D0016020cellular_componentmembrane
D0022848molecular_functionacetylcholine-gated monoatomic cation-selective channel activity
D0034220biological_processmonoatomic ion transmembrane transport
D0035094biological_processresponse to nicotine
D0042391biological_processregulation of membrane potential
D0042802molecular_functionidentical protein binding
D0043005cellular_componentneuron projection
D0045202cellular_componentsynapse
D0046872molecular_functionmetal ion binding
D0050877biological_processnervous system process
D0060078biological_processregulation of postsynaptic membrane potential
D0060079biological_processexcitatory postsynaptic potential
D0098794cellular_componentpostsynapse
E0004888molecular_functiontransmembrane signaling receptor activity
E0005216molecular_functionmonoatomic ion channel activity
E0005230molecular_functionextracellular ligand-gated monoatomic ion channel activity
E0005515molecular_functionprotein binding
E0006811biological_processmonoatomic ion transport
E0007165biological_processsignal transduction
E0007271biological_processsynaptic transmission, cholinergic
E0015464molecular_functionacetylcholine receptor activity
E0016020cellular_componentmembrane
E0022848molecular_functionacetylcholine-gated monoatomic cation-selective channel activity
E0034220biological_processmonoatomic ion transmembrane transport
E0035094biological_processresponse to nicotine
E0042391biological_processregulation of membrane potential
E0042802molecular_functionidentical protein binding
E0043005cellular_componentneuron projection
E0045202cellular_componentsynapse
E0046872molecular_functionmetal ion binding
E0050877biological_processnervous system process
E0060078biological_processregulation of postsynaptic membrane potential
E0060079biological_processexcitatory postsynaptic potential
E0098794cellular_componentpostsynapse
Functional Information from PDB Data
site_idAC1
Number of Residues7
DetailsBINDING SITE FOR RESIDUE EPE A1206
ChainResidue
ATYR91
ATRP145
ATYR186
ACYS188
ATYR193
BGLN36
BTYR53

site_idAC2
Number of Residues7
DetailsBINDING SITE FOR RESIDUE EPE B1206
ChainResidue
BVAL146
BTYR186
CGLN36
CTYR53
CSER165
BTYR91
BTRP145

site_idAC3
Number of Residues6
DetailsBINDING SITE FOR RESIDUE EPE C1206
ChainResidue
CTYR91
CTRP145
CTYR186
CTYR193
DTYR53
DSER165

site_idAC4
Number of Residues8
DetailsBINDING SITE FOR RESIDUE EPE D1206
ChainResidue
DTYR91
DTRP145
DTYR186
DSER187
DCYS188
DTYR193
ETHR34
ETYR53

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PDB entries from 2024-05-01

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