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2BQU

DNA Adduct Bypass Polymerization by Sulfolobus solfataricus Dpo4. Analysis and Crystal Structures of Multiple Base-Pair Substitution and Frameshift Products with the Adduct 1,N2-Ethenoguanine

Functional Information from GO Data
ChainGOidnamespacecontents
A0000287molecular_functionmagnesium ion binding
A0003677molecular_functionDNA binding
A0003684molecular_functiondamaged DNA binding
A0003887molecular_functionDNA-directed DNA polymerase activity
A0005737cellular_componentcytoplasm
A0006260biological_processDNA replication
A0006261biological_processDNA-templated DNA replication
A0006281biological_processDNA repair
A0006974biological_processDNA damage response
A0042276biological_processerror-prone translesion synthesis
A0046872molecular_functionmetal ion binding
Functional Information from PDB Data
site_idAC1
Number of Residues5
DetailsBINDING SITE FOR RESIDUE CA A1343
ChainResidue
AASP7
AASP105
AGLU106
ADAD1342
ACA1344

site_idAC2
Number of Residues5
DetailsBINDING SITE FOR RESIDUE CA A1344
ChainResidue
ACA1343
AASP7
APHE8
AASP105
ADAD1342

site_idAC3
Number of Residues6
DetailsBINDING SITE FOR RESIDUE CA A1345
ChainResidue
AALA181
AILE186
AHOH2045
PHOH2006
PHOH2014
PHOH2015

site_idAC4
Number of Residues20
DetailsBINDING SITE FOR RESIDUE DAD A1342
ChainResidue
APHE8
ATYR10
APHE11
ATYR12
AALA44
ATHR45
AARG51
AASP105
ALYS159
ACA1343
ACA1344
AHOH2084
AHOH2085
AHOH2086
AHOH2087
AHOH2088
AHOH2090
PDC13
TDT4
TGNE5

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsACT_SITE:
ChainResidueDetails
AGLU106

site_idSWS_FT_FI2
Number of Residues2
DetailsBINDING:
ChainResidueDetails
AASP7
AASP105

site_idSWS_FT_FI3
Number of Residues1
DetailsSITE: Substrate discrimination
ChainResidueDetails
ATYR12

226707

PDB entries from 2024-10-30

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