2BQ8

Crystal structure of human purple acid phosphatase with an inhibitory conformation of the repression loop

Functional Information from GO Data

Chain	GOid	namespace	contents
X	0003993	molecular_function	acid phosphatase activity
X	0005764	cellular_component	lysosome
X	0005829	cellular_component	cytosol
X	0006809	biological_process	nitric oxide biosynthetic process
X	0008198	molecular_function	ferrous iron binding
X	0008199	molecular_function	ferric iron binding
X	0010936	biological_process	negative regulation of macrophage cytokine production
X	0016020	cellular_component	membrane
X	0016311	biological_process	dephosphorylation
X	0016787	molecular_function	hydrolase activity
X	0032496	biological_process	response to lipopolysaccharide
X	0032691	biological_process	negative regulation of interleukin-1 beta production
X	0032695	biological_process	negative regulation of interleukin-12 production
X	0032720	biological_process	negative regulation of tumor necrosis factor production
X	0032929	biological_process	negative regulation of superoxide anion generation
X	0034097	biological_process	response to cytokine
X	0042554	biological_process	superoxide anion generation
X	0045019	biological_process	negative regulation of nitric oxide biosynthetic process
X	0045453	biological_process	bone resorption
X	0046872	molecular_function	metal ion binding
X	0050728	biological_process	negative regulation of inflammatory response
X	0050830	biological_process	defense response to Gram-positive bacterium
X	0060349	biological_process	bone morphogenesis

Functional Information from PDB Data

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI2
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269\|PubMed:15993892

Chain	Residue	Details
X	ASN95

site_id	SWS_FT_FI3
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
X	ASN126