2BPQ
Anthranilate phosphoribosyltransferase (TrpD) from Mycobacterium tuberculosis (Apo structure)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000162 | biological_process | tryptophan biosynthetic process |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0004048 | molecular_function | anthranilate phosphoribosyltransferase activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005829 | cellular_component | cytosol |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0016757 | molecular_function | glycosyltransferase activity |
| A | 0016763 | molecular_function | pentosyltransferase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000162 | biological_process | tryptophan biosynthetic process |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0004048 | molecular_function | anthranilate phosphoribosyltransferase activity |
| B | 0005576 | cellular_component | extracellular region |
| B | 0005829 | cellular_component | cytosol |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0016757 | molecular_function | glycosyltransferase activity |
| B | 0016763 | molecular_function | pentosyltransferase activity |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE BEN A 1369 |
| Chain | Residue |
| A | THR70 |
| A | MET71 |
| A | LYS72 |
| A | ASP225 |
| A | HOH2140 |
| B | THR35 |
| B | ASN37 |
| B | GOL1376 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE BEN B 1374 |
| Chain | Residue |
| B | MET69 |
| B | THR70 |
| B | MET71 |
| B | LYS72 |
| B | ASP225 |
| A | ASN37 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE BEN B 1375 |
| Chain | Residue |
| B | GLY80 |
| B | THR353 |
| B | ALA355 |
| B | HOH2018 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 1370 |
| Chain | Residue |
| A | PHE274 |
| A | ASP275 |
| A | GLY278 |
| A | PHE279 |
| A | TRP336 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 1376 |
| Chain | Residue |
| A | THR70 |
| A | PRO199 |
| A | BEN1369 |
| A | HOH2073 |
| B | THR35 |
| B | ASP36 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00211 |
| Chain | Residue | Details |
| A | GLY107 | |
| B | GLY107 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | GLY110 | |
| B | ASN117 | |
| B | SER119 | |
| B | LYS135 | |
| B | ASN138 | |
| B | ARG193 | |
| B | ASP251 | |
| B | GLU252 | |
| A | ASN117 | |
| A | SER119 | |
| A | LYS135 | |
| A | ASN138 | |
| A | ARG193 | |
| A | ASP251 | |
| A | GLU252 | |
| B | GLY110 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00211, ECO:0000269|PubMed:16337227, ECO:0000269|PubMed:23363292, ECO:0000269|Ref.4, ECO:0000269|Ref.5 |
| Chain | Residue | Details |
| A | THR115 | |
| A | GLY147 | |
| B | THR115 | |
| B | GLY147 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | MOD_RES: N-acetylalanine => ECO:0007744|PubMed:21969609 |
| Chain | Residue | Details |
| A | ALA2 | |
| B | ALA2 |
