2BJN
X-ray Structure of human TPC6
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005783 | cellular_component | endoplasmic reticulum |
| A | 0005794 | cellular_component | Golgi apparatus |
| A | 0005801 | cellular_component | cis-Golgi network |
| A | 0005802 | cellular_component | trans-Golgi network |
| A | 0005829 | cellular_component | cytosol |
| A | 0006888 | biological_process | endoplasmic reticulum to Golgi vesicle-mediated transport |
| A | 0006901 | biological_process | vesicle coating |
| A | 0007399 | biological_process | nervous system development |
| A | 0030008 | cellular_component | TRAPP complex |
| A | 0043087 | biological_process | regulation of GTPase activity |
| A | 0048193 | biological_process | Golgi vesicle transport |
| A | 0099022 | biological_process | vesicle tethering |
| B | 0005515 | molecular_function | protein binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005783 | cellular_component | endoplasmic reticulum |
| B | 0005794 | cellular_component | Golgi apparatus |
| B | 0005801 | cellular_component | cis-Golgi network |
| B | 0005802 | cellular_component | trans-Golgi network |
| B | 0005829 | cellular_component | cytosol |
| B | 0006888 | biological_process | endoplasmic reticulum to Golgi vesicle-mediated transport |
| B | 0006901 | biological_process | vesicle coating |
| B | 0007399 | biological_process | nervous system development |
| B | 0030008 | cellular_component | TRAPP complex |
| B | 0043087 | biological_process | regulation of GTPase activity |
| B | 0048193 | biological_process | Golgi vesicle transport |
| B | 0099022 | biological_process | vesicle tethering |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A1160 |
| Chain | Residue |
| A | ARG33 |
| A | LYS37 |
| A | ASN40 |
| A | ARG44 |
| A | HOH2055 |
| A | HOH2056 |
| A | HOH2057 |
| B | GLN47 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 A1161 |
| Chain | Residue |
| A | GLU28 |
| A | VAL29 |
| A | ASN31 |
| A | GLY32 |
| A | ARG33 |
| A | CYS34 |
| A | ILE35 |
| A | GOL1163 |
| A | TYR21 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B1160 |
| Chain | Residue |
| B | ASN89 |
| B | GLN91 |
| B | ILE93 |
| B | MET156 |
| B | ILE157 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B1161 |
| Chain | Residue |
| A | GLY1 |
| B | PHE53 |
| B | THR54 |
| B | ARG59 |
| B | HOH2065 |
| B | HOH2066 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 B1162 |
| Chain | Residue |
| A | GLN47 |
| B | ARG33 |
| B | LYS37 |
| B | ASN40 |
| B | ARG44 |
| B | HOH2067 |
| B | HOH2068 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A1162 |
| Chain | Residue |
| A | GLU39 |
| A | SER118 |
| A | ALA122 |
| A | THR142 |
| A | ALA143 |
| A | HOH2058 |
| B | LYS138 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A1163 |
| Chain | Residue |
| A | TYR21 |
| A | ILE35 |
| A | GLU115 |
| A | SO41161 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL B1163 |
| Chain | Residue |
| B | LYS68 |
| B | CYS71 |
| B | LYS72 |
| B | ILE83 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B1164 |
| Chain | Residue |
| A | LYS138 |
| B | GLU39 |
| B | SER118 |
| B | ALA122 |
| B | THR142 |
| B | ALA143 |
