2BJ0

Crystal Structure of AChBP from Bulinus truncatus revals the conserved structural scaffold and sites of variation in nicotinic acetylcholine receptors

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004888	molecular_function	transmembrane signaling receptor activity
A	0005216	molecular_function	monoatomic ion channel activity
A	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
A	0006811	biological_process	monoatomic ion transport
A	0016020	cellular_component	membrane
A	0034220	biological_process	monoatomic ion transmembrane transport
B	0004888	molecular_function	transmembrane signaling receptor activity
B	0005216	molecular_function	monoatomic ion channel activity
B	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
B	0006811	biological_process	monoatomic ion transport
B	0016020	cellular_component	membrane
B	0034220	biological_process	monoatomic ion transmembrane transport
C	0004888	molecular_function	transmembrane signaling receptor activity
C	0005216	molecular_function	monoatomic ion channel activity
C	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
C	0006811	biological_process	monoatomic ion transport
C	0016020	cellular_component	membrane
C	0034220	biological_process	monoatomic ion transmembrane transport
D	0004888	molecular_function	transmembrane signaling receptor activity
D	0005216	molecular_function	monoatomic ion channel activity
D	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
D	0006811	biological_process	monoatomic ion transport
D	0016020	cellular_component	membrane
D	0034220	biological_process	monoatomic ion transmembrane transport
E	0004888	molecular_function	transmembrane signaling receptor activity
E	0005216	molecular_function	monoatomic ion channel activity
E	0005230	molecular_function	extracellular ligand-gated monoatomic ion channel activity
E	0006811	biological_process	monoatomic ion transport
E	0016020	cellular_component	membrane
E	0034220	biological_process	monoatomic ion transmembrane transport

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	BINDING SITE FOR RESIDUE CXS A1204

Chain	Residue
A	TRP142
B	VAL103
B	VAL113
A	TYR184
A	SER185
A	CYS186
A	CYS187
A	TYR191
A	HOH2034
B	TRP51
B	GLN53

---

site_id	AC2
Number of Residues	11
Details	BINDING SITE FOR RESIDUE CXS B1204

Chain	Residue
B	TRP142
B	TYR184
B	SER185
B	CYS186
B	CYS187
B	TYR191
B	HOH2039
C	TRP51
C	GLN53
C	VAL103
C	VAL113

---

site_id	AC3
Number of Residues	11
Details	BINDING SITE FOR RESIDUE CXS C1204

Chain	Residue
C	TYR88
C	TRP142
C	TYR184
C	SER185
C	CYS186
C	TYR191
D	TRP51
D	GLN53
D	VAL103
D	VAL113
D	HOH2048

---

site_id	AC4
Number of Residues	11
Details	BINDING SITE FOR RESIDUE CXS D1204

Chain	Residue
D	TRP142
D	TYR184
D	SER185
D	CYS186
D	CYS187
D	TYR191
D	HOH2036
E	TRP51
E	GLN53
E	VAL103
E	VAL113

---