Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

2BHS

Crystal Structure of Cysteine Synthase B

Functional Information from GO Data
ChainGOidnamespacecontents
A0004124molecular_functioncysteine synthase activity
A0005515molecular_functionprotein binding
A0005737cellular_componentcytoplasm
A0006535biological_processcysteine biosynthetic process from serine
A0016226biological_processiron-sulfur cluster assembly
A0016740molecular_functiontransferase activity
A0016765molecular_functiontransferase activity, transferring alkyl or aryl (other than methyl) groups
A0016829molecular_functionlyase activity
A0019344biological_processcysteine biosynthetic process
A0019345biological_processcysteine biosynthetic process via S-sulfo-L-cysteine
A0019450biological_processL-cysteine catabolic process to pyruvate
A0030170molecular_functionpyridoxal phosphate binding
A0042803molecular_functionprotein homodimerization activity
A0080146molecular_functionL-cysteine desulfhydrase activity
B0004124molecular_functioncysteine synthase activity
B0005515molecular_functionprotein binding
B0005737cellular_componentcytoplasm
B0006535biological_processcysteine biosynthetic process from serine
B0016226biological_processiron-sulfur cluster assembly
B0016740molecular_functiontransferase activity
B0016765molecular_functiontransferase activity, transferring alkyl or aryl (other than methyl) groups
B0016829molecular_functionlyase activity
B0019344biological_processcysteine biosynthetic process
B0019345biological_processcysteine biosynthetic process via S-sulfo-L-cysteine
B0019450biological_processL-cysteine catabolic process to pyruvate
B0030170molecular_functionpyridoxal phosphate binding
B0042803molecular_functionprotein homodimerization activity
B0080146molecular_functionL-cysteine desulfhydrase activity
C0004124molecular_functioncysteine synthase activity
C0005515molecular_functionprotein binding
C0005737cellular_componentcytoplasm
C0006535biological_processcysteine biosynthetic process from serine
C0016226biological_processiron-sulfur cluster assembly
C0016740molecular_functiontransferase activity
C0016765molecular_functiontransferase activity, transferring alkyl or aryl (other than methyl) groups
C0016829molecular_functionlyase activity
C0019344biological_processcysteine biosynthetic process
C0019345biological_processcysteine biosynthetic process via S-sulfo-L-cysteine
C0019450biological_processL-cysteine catabolic process to pyruvate
C0030170molecular_functionpyridoxal phosphate binding
C0042803molecular_functionprotein homodimerization activity
C0080146molecular_functionL-cysteine desulfhydrase activity
D0004124molecular_functioncysteine synthase activity
D0005515molecular_functionprotein binding
D0005737cellular_componentcytoplasm
D0006535biological_processcysteine biosynthetic process from serine
D0016226biological_processiron-sulfur cluster assembly
D0016740molecular_functiontransferase activity
D0016765molecular_functiontransferase activity, transferring alkyl or aryl (other than methyl) groups
D0016829molecular_functionlyase activity
D0019344biological_processcysteine biosynthetic process
D0019345biological_processcysteine biosynthetic process via S-sulfo-L-cysteine
D0019450biological_processL-cysteine catabolic process to pyruvate
D0030170molecular_functionpyridoxal phosphate binding
D0042803molecular_functionprotein homodimerization activity
D0080146molecular_functionL-cysteine desulfhydrase activity
Functional Information from PDB Data
site_idAC1
Number of Residues18
DetailsBINDING SITE FOR RESIDUE PLP A 320
ChainResidue
ALYS41
AILE209
ASER255
ACYS280
AASP281
ATYR286
AHOH2043
AHOH2070
AHOH2071
AHOH2072
AASN71
ASER172
AGLY174
ATHR175
ATHR176
AGLY177
ATHR178
AGLY208

site_idAC2
Number of Residues18
DetailsBINDING SITE FOR RESIDUE PLP B 320
ChainResidue
BLYS41
BASN71
BSER172
BGLY174
BTHR175
BTHR176
BGLY177
BTHR178
BGLY208
BILE209
BSER255
BCYS280
BASP281
BTYR286
BHOH2082
BHOH2083
BHOH2084
BHOH2085

site_idAC3
Number of Residues17
DetailsBINDING SITE FOR RESIDUE PLP C 320
ChainResidue
CLYS41
CASN71
CSER172
CGLY174
CTHR175
CTHR176
CGLY177
CTHR178
CGLY208
CILE209
CSER255
CCYS280
CASP281
CTYR286
CHOH2052
CHOH2053
CHOH2054

site_idAC4
Number of Residues18
DetailsBINDING SITE FOR RESIDUE PLP D 320
ChainResidue
DLYS41
DASN71
DSER172
DGLY174
DTHR175
DTHR176
DGLY177
DTHR178
DGLY208
DILE209
DSER255
DCYS280
DASP281
DTYR286
DHOH2054
DHOH2055
DHOH2056
DHOH2057

Functional Information from PROSITE/UniProt
site_idPS00901
Number of Residues19
DetailsCYS_SYNTHASE Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. KlEgnn.PAgSVKdRaAlsM
ChainResidueDetails
ALYS30-MET48

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues8
DetailsBINDING: BINDING => ECO:0000269|PubMed:15952768
ChainResidueDetails
AASN71
ASER255
BASN71
BSER255
CASN71
CSER255
DASN71
DSER255

site_idSWS_FT_FI2
Number of Residues4
DetailsBINDING:
ChainResidueDetails
AGLY174
BGLY174
CGLY174
DGLY174

site_idSWS_FT_FI3
Number of Residues4
DetailsMOD_RES: N6-(pyridoxal phosphate)lysine
ChainResidueDetails
ALYS41
BLYS41
CLYS41
DLYS41

Catalytic Information from CSA
site_idCSA1
Number of Residues2
DetailsAnnotated By Reference To The Literature 1oas
ChainResidueDetails
ASER255
ALYS41

site_idCSA2
Number of Residues2
DetailsAnnotated By Reference To The Literature 1oas
ChainResidueDetails
BSER255
BLYS41

site_idCSA3
Number of Residues2
DetailsAnnotated By Reference To The Literature 1oas
ChainResidueDetails
CSER255
CLYS41

site_idCSA4
Number of Residues2
DetailsAnnotated By Reference To The Literature 1oas
ChainResidueDetails
DSER255
DLYS41

site_idCSA5
Number of Residues1
DetailsAnnotated By Reference To The Literature 1oas
ChainResidueDetails
ALYS41

site_idCSA6
Number of Residues1
DetailsAnnotated By Reference To The Literature 1oas
ChainResidueDetails
BLYS41

site_idCSA7
Number of Residues1
DetailsAnnotated By Reference To The Literature 1oas
ChainResidueDetails
CLYS41

site_idCSA8
Number of Residues1
DetailsAnnotated By Reference To The Literature 1oas
ChainResidueDetails
DLYS41

221371

PDB entries from 2024-06-19

PDB statisticsPDBj update infoContact PDBjnumon