2BF8
Crystal structure of SUMO modified ubiquitin conjugating enzyme E2- 25K
Functional Information from PROSITE/UniProt
| site_id | PS00183 |
| Number of Residues | 17 |
| Details | UBC_1 Ubiquitin-conjugating (UBC) active site signature. WHPNIssvtGaICLdiL |
| Chain | Residue | Details |
| A | TRP80-LEU96 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | SITE: Interaction with PIAS2 |
| Chain | Residue | Details |
| B | PHE36 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| B | SER32 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733 |
| Chain | Residue | Details |
| B | LYS23 | |
| B | LYS39 | |
| B | LYS45 | |
| B | LYS46 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins) => ECO:0000269|PubMed:27068747 |
| Chain | Residue | Details |
| A | GLU15 | |
| B | GLY97 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1) |
| Chain | Residue | Details |
| B | LYS25 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:25755297, ECO:0007744|PubMed:28112733 |
| Chain | Residue | Details |
| B | LYS37 |
