2BEP

Crystal structure of ubiquitin conjugating enzyme E2-25K

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE BME A1156

Chain	Residue
A	CYS92
A	ASP124

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Functional Information from PROSITE/UniProt

site_id	PS00183
Number of Residues	17
Details	UBC_1 Ubiquitin-conjugating (UBC) active site signature. WHPNIssvtGaICLdiL

Chain	Residue	Details
A	TRP80-LEU96

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Glycyl thioester intermediate => ECO:0000255|PROSITE-ProRule:PRU00388

Chain	Residue	Details
A	CYS92

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: N-acetylalanine => ECO:0000250|UniProtKB:P61086

Chain	Residue	Details
A	ALA2

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site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: N6-acetyllysine; alternate => ECO:0000250|UniProtKB:P61086

Chain	Residue	Details
A	LYS14

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site_id	SWS_FT_FI4
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1); alternate => ECO:0000250|UniProtKB:P61086

Chain	Residue	Details
A	LYS14

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