2BCP

Structural Analysis of Streptococcus pyogenes NADH oxidase: C44S Nox with Azide

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016491	molecular_function	oxidoreductase activity
B	0016491	molecular_function	oxidoreductase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE AZI A 668

Chain	Residue
A	HIS11
A	LEU42
A	GLY43
A	SER44
A	FAD601
B	PHE436

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE AZI B 669

Chain	Residue
B	SER44
B	FAD602
A	PHE436
B	HIS11
B	GLY43

---

site_id	AC3
Number of Residues	34
Details	BINDING SITE FOR RESIDUE FAD A 601

Chain	Residue
A	VAL7
A	GLY8
A	ASN10
A	HIS11
A	ALA12
A	ASP34
A	GLN35
A	ASN36
A	GLY43
A	SER44
A	VAL81
A	ALA110
A	THR111
A	GLY112
A	SER113
A	LYS143
A	TYR170
A	PHE255
A	LEU261
A	GLY291
A	ASP292
A	ALA308
A	LEU309
A	ALA310
A	SER311
A	AZI668
A	HOH675
A	HOH681
A	HOH689
A	HOH691
A	HOH693
A	HOH802
B	PHE436
B	LEU437

---

site_id	AC4
Number of Residues	34
Details	BINDING SITE FOR RESIDUE FAD B 602

Chain	Residue
A	PHE436
A	HOH702
B	GLY8
B	ASN10
B	HIS11
B	ALA12
B	ASP34
B	GLN35
B	ASN36
B	GLY43
B	SER44
B	PRO80
B	VAL81
B	ALA110
B	THR111
B	GLY112
B	SER113
B	VAL142
B	LYS143
B	TYR170
B	PHE255
B	GLY291
B	ASP292
B	ALA308
B	LEU309
B	ALA310
B	SER311
B	AZI669
B	HOH674
B	HOH686
B	HOH700
B	HOH718
B	HOH728
B	HOH920

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"UniProtKB","id":"P37062","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Active site: {"description":"Redox-active","evidences":[{"source":"PubMed","id":"26506002","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2BC0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	22
Details	Binding site: {"evidences":[{"source":"PubMed","id":"26506002","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2BC0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2BC1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2BCP","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"26506002","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2BC0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"26506002","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2BC0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2BCP","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"26506002","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2BC1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2BCP","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P37062","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"26506002","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2BC0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2BC1","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	2
Details	Modified residue: {"description":"Cysteine sulfinic acid (-SO2H)","evidences":[{"source":"PubMed","id":"26506002","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2BC0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 1get

Chain	Residue	Details
A	HIS439
A	TYR444

---

site_id	CSA2
Number of Residues	2
Details	Annotated By Reference To The Literature 1get

Chain	Residue	Details
B	HIS439
B	TYR444

---