Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005515 | molecular_function | protein binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005615 | cellular_component | extracellular space |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006824 | biological_process | cobalt ion transport |
| A | 0009897 | cellular_component | external side of plasma membrane |
| A | 0015889 | biological_process | cobalamin transport |
| A | 0031419 | molecular_function | cobalamin binding |
| A | 0043202 | cellular_component | lysosomal lumen |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0140355 | molecular_function | cargo receptor ligand activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005576 | cellular_component | extracellular region |
| B | 0005615 | cellular_component | extracellular space |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0006824 | biological_process | cobalt ion transport |
| B | 0009897 | cellular_component | external side of plasma membrane |
| B | 0015889 | biological_process | cobalamin transport |
| B | 0031419 | molecular_function | cobalamin binding |
| B | 0043202 | cellular_component | lysosomal lumen |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0140355 | molecular_function | cargo receptor ligand activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR RESIDUE B12 A 0 |
| Chain | Residue |
| A | GLY85 |
| A | ASN224 |
| A | TYR226 |
| A | SER227 |
| A | MET270 |
| A | GLN273 |
| A | SER357 |
| A | LEU358 |
| A | SER359 |
| A | GLY360 |
| A | PRO361 |
| A | GLN86 |
| A | TYR362 |
| A | LEU363 |
| A | PHE376 |
| A | TRP377 |
| A | GLN378 |
| A | LEU379 |
| A | LEU387 |
| A | LEU388 |
| A | GLY390 |
| A | TRP409 |
| A | THR134 |
| A | SER135 |
| A | TYR137 |
| A | GLN138 |
| A | HIS172 |
| A | HIS173 |
| A | ASP176 |
| site_id | AC2 |
| Number of Residues | 28 |
| Details | BINDING SITE FOR RESIDUE B12 B 410 |
| Chain | Residue |
| B | GLY85 |
| B | GLN86 |
| B | THR134 |
| B | TYR137 |
| B | GLN138 |
| B | HIS172 |
| B | HIS173 |
| B | ASP176 |
| B | ASN224 |
| B | TYR226 |
| B | SER227 |
| B | MET270 |
| B | GLN273 |
| B | SER357 |
| B | LEU358 |
| B | SER359 |
| B | GLY360 |
| B | PRO361 |
| B | TYR362 |
| B | LEU363 |
| B | PHE376 |
| B | TRP377 |
| B | LEU379 |
| B | LEU387 |
| B | LEU388 |
| B | GLY390 |
| B | TRP409 |
| B | HOH414 |
Functional Information from PROSITE/UniProt
| site_id | PS00468 |
| Number of Residues | 14 |
| Details | COBALAMIN_BINDING Eukaryotic cobalamin-binding proteins signature. SVDTAAMAgLAFTC |
| Chain | Residue | Details |
| A | SER174-CYS187 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| B | GLN86 | |
| B | SER227 | |
| A | GLN86 | |
| A | SER227 | |
| Chain | Residue | Details |
| B | ASN224 | |
| B | TRP377 | |
| A | THR134 | |
| A | ASN224 | |
| A | TRP377 | |
| B | THR134 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | BINDING: axial binding residue |
| Chain | Residue | Details |
| A | HIS172 | |
| B | HIS172 | |
| Chain | Residue | Details |
| A | GLN273 | |
| B | GLN273 | |
