2BA1

Archaeal exosome core

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000178	cellular_component	exosome (RNase complex)
A	0003676	molecular_function	nucleic acid binding
A	0003723	molecular_function	RNA binding
A	0005737	cellular_component	cytoplasm
A	0006396	biological_process	RNA processing
A	0006401	biological_process	RNA catabolic process
A	0008270	molecular_function	zinc ion binding
A	0046872	molecular_function	metal ion binding
B	0000178	cellular_component	exosome (RNase complex)
B	0003676	molecular_function	nucleic acid binding
B	0003723	molecular_function	RNA binding
B	0005737	cellular_component	cytoplasm
B	0006396	biological_process	RNA processing
B	0006401	biological_process	RNA catabolic process
B	0008270	molecular_function	zinc ion binding
B	0046872	molecular_function	metal ion binding
C	0000178	cellular_component	exosome (RNase complex)
C	0003676	molecular_function	nucleic acid binding
C	0003723	molecular_function	RNA binding
C	0005737	cellular_component	cytoplasm
C	0006396	biological_process	RNA processing
C	0006401	biological_process	RNA catabolic process
C	0008270	molecular_function	zinc ion binding
C	0046872	molecular_function	metal ion binding
D	0000175	molecular_function	3'-5'-RNA exonuclease activity
D	0000177	cellular_component	cytoplasmic exosome (RNase complex)
D	0000178	cellular_component	exosome (RNase complex)
D	0004527	molecular_function	exonuclease activity
D	0005737	cellular_component	cytoplasm
D	0006401	biological_process	RNA catabolic process
D	0016075	biological_process	rRNA catabolic process
D	0016896	molecular_function	RNA exonuclease activity, producing 5'-phosphomonoesters
E	0000175	molecular_function	3'-5'-RNA exonuclease activity
E	0000177	cellular_component	cytoplasmic exosome (RNase complex)
E	0000178	cellular_component	exosome (RNase complex)
E	0004527	molecular_function	exonuclease activity
E	0005737	cellular_component	cytoplasm
E	0006401	biological_process	RNA catabolic process
E	0016075	biological_process	rRNA catabolic process
E	0016896	molecular_function	RNA exonuclease activity, producing 5'-phosphomonoesters
F	0000175	molecular_function	3'-5'-RNA exonuclease activity
F	0000177	cellular_component	cytoplasmic exosome (RNase complex)
F	0000178	cellular_component	exosome (RNase complex)
F	0004527	molecular_function	exonuclease activity
F	0005737	cellular_component	cytoplasm
F	0006401	biological_process	RNA catabolic process
F	0016075	biological_process	rRNA catabolic process
F	0016896	molecular_function	RNA exonuclease activity, producing 5'-phosphomonoesters
G	0000178	cellular_component	exosome (RNase complex)
G	0005737	cellular_component	cytoplasm
G	0006401	biological_process	RNA catabolic process
H	0000178	cellular_component	exosome (RNase complex)
H	0005737	cellular_component	cytoplasm
H	0006401	biological_process	RNA catabolic process
I	0000178	cellular_component	exosome (RNase complex)
I	0005737	cellular_component	cytoplasm
I	0006401	biological_process	RNA catabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 201

Chain	Residue
A	CYS143
A	CYS146
A	CYS159
A	CYS162

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 202

Chain	Residue
B	CYS143
B	CYS146
B	CYS159
B	CYS162

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN C 203

Chain	Residue
C	CYS146
C	CYS159
C	CYS162
C	CYS143

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00975, ECO:0000269|PubMed:16285927, ECO:0000269|PubMed:20392821

Chain	Residue	Details
A	CYS143
B	CYS146
B	CYS159
B	CYS162
A	CYS146
A	CYS159
A	CYS162
C	CYS143
C	CYS146
C	CYS159
C	CYS162
B	CYS143

---