2B8H

A/NWS/whale/Maine/1/84 (H1N9) reassortant influenza virus neuraminidase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004308	molecular_function	exo-alpha-sialidase activity
A	0005975	biological_process	carbohydrate metabolic process
A	0016020	cellular_component	membrane
A	0033644	cellular_component	host cell membrane
A	0046761	biological_process	viral budding from plasma membrane
A	0055036	cellular_component	virion membrane
B	0004308	molecular_function	exo-alpha-sialidase activity
B	0005975	biological_process	carbohydrate metabolic process
B	0016020	cellular_component	membrane
B	0033644	cellular_component	host cell membrane
B	0046761	biological_process	viral budding from plasma membrane
B	0055036	cellular_component	virion membrane
C	0004308	molecular_function	exo-alpha-sialidase activity
C	0005975	biological_process	carbohydrate metabolic process
C	0016020	cellular_component	membrane
C	0033644	cellular_component	host cell membrane
C	0046761	biological_process	viral budding from plasma membrane
C	0055036	cellular_component	virion membrane
D	0004308	molecular_function	exo-alpha-sialidase activity
D	0005975	biological_process	carbohydrate metabolic process
D	0016020	cellular_component	membrane
D	0033644	cellular_component	host cell membrane
D	0046761	biological_process	viral budding from plasma membrane
D	0055036	cellular_component	virion membrane

Functional Information from PROSITE/UniProt

site_id	PS00022
Number of Residues	12
Details	EGF_1 EGF-like domain signature 1. CsCygEqaGVtC

Chain	Residue	Details
A	CYS279-CYS290

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: Proton donor/acceptor => ECO:0000255|HAMAP-Rule:MF_04071

Chain	Residue	Details
A	ASP151
B	ASP151
C	ASP151
D	ASP151

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site_id	SWS_FT_FI2
Number of Residues	4
Details	ACT_SITE: Nucleophile => ECO:0000255|HAMAP-Rule:MF_04071

Chain	Residue	Details
A	TYR405
B	TYR405
C	TYR405
D	TYR405

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site_id	SWS_FT_FI3
Number of Residues	20
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_04071

Chain	Residue	Details
A	ARG118
B	ARG371
C	ARG118
C	ARG152
C	GLU277
C	ARG293
C	ARG371
D	ARG118
D	ARG152
D	GLU277
D	ARG293
A	ARG152
D	ARG371
A	GLU277
A	ARG293
A	ARG371
B	ARG118
B	ARG152
B	GLU277
B	ARG293

---

site_id	SWS_FT_FI4
Number of Residues	16
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_04071, ECO:0000269|PubMed:7994573

Chain	Residue	Details
A	ASP294
C	GLY298
C	ASP325
C	ASN347
D	ASP294
D	GLY298
D	ASP325
D	ASN347
A	GLY298
A	ASP325
A	ASN347
B	ASP294
B	GLY298
B	ASP325
B	ASN347
C	ASP294

---

site_id	SWS_FT_FI5
Number of Residues	4
Details	CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04071, ECO:0000269|PubMed:7517697, ECO:0000269|PubMed:7994573

Chain	Residue	Details
A	ASN86
B	ASN86
C	ASN86
D	ASN86

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site_id	SWS_FT_FI6
Number of Residues	4
Details	CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04071, ECO:0000269|PubMed:7994573

Chain	Residue	Details
A	ASN146
B	ASN146
C	ASN146
D	ASN146

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site_id	SWS_FT_FI7
Number of Residues	4
Details	CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04071

Chain	Residue	Details
A	ASN201
B	ASN201
C	ASN201
D	ASN201

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 1a4g

Chain	Residue	Details
A	GLU278
A	ASP151

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site_id	CSA2
Number of Residues	2
Details	Annotated By Reference To The Literature 1a4g

Chain	Residue	Details
B	GLU278
B	ASP151

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site_id	CSA3
Number of Residues	2
Details	Annotated By Reference To The Literature 1a4g

Chain	Residue	Details
C	GLU278
C	ASP151

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site_id	CSA4
Number of Residues	2
Details	Annotated By Reference To The Literature 1a4g

Chain	Residue	Details
D	GLU278
D	ASP151

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