2B7O
The Structure of 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase from Mycobacterium tuberculosis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003849 | molecular_function | 3-deoxy-7-phosphoheptulonate synthase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| A | 0009274 | cellular_component | peptidoglycan-based cell wall |
| A | 0009423 | biological_process | chorismate biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0030145 | molecular_function | manganese ion binding |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051260 | biological_process | protein homooligomerization |
| B | 0003849 | molecular_function | 3-deoxy-7-phosphoheptulonate synthase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0008652 | biological_process | amino acid biosynthetic process |
| B | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| B | 0009274 | cellular_component | peptidoglycan-based cell wall |
| B | 0009423 | biological_process | chorismate biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0030145 | molecular_function | manganese ion binding |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0051260 | biological_process | protein homooligomerization |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MN A 700 |
| Chain | Residue |
| A | CYS87 |
| A | HIS369 |
| A | GLU411 |
| A | ASP441 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 2001 |
| Chain | Residue |
| A | ARG135 |
| A | SER136 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 2002 |
| Chain | Residue |
| B | ARG284 |
| B | PRO134 |
| B | ARG135 |
| B | SER136 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MN B 701 |
| Chain | Residue |
| B | CYS87 |
| B | HIS369 |
| B | GLU411 |
| B | ASP441 |
| site_id | AC5 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE PEP A 702 |
| Chain | Residue |
| A | ARG126 |
| A | GLU248 |
| A | TRP280 |
| A | GLY282 |
| A | GLU283 |
| A | ARG284 |
| A | LYS306 |
| A | ARG337 |
| A | HIS369 |
| A | HOH2115 |
| site_id | AC6 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE CE1 A 1001 |
| Chain | Residue |
| A | PHE91 |
| A | MSE92 |
| A | ASN94 |
| A | ARG171 |
| A | ALA174 |
| A | ASN175 |
| B | LEU12 |
| B | SER54 |
| B | ASN175 |
| B | HOH2088 |
| site_id | AC7 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE PEP B 703 |
| Chain | Residue |
| B | ARG126 |
| B | GLU248 |
| B | TRP280 |
| B | GLY282 |
| B | GLU283 |
| B | LYS306 |
| B | ARG337 |
| B | HIS369 |
| B | GLU411 |
| B | HOH2030 |
| B | HOH2031 |
| B | HOH2034 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 13 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16288916","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2B7O","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
