2B7N
Crystal structure of quinolinic acid phosphoribosyltransferase from Helicobacter pylori
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004514 | molecular_function | nicotinate-nucleotide diphosphorylase (carboxylating) activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0009435 | biological_process | NAD+ biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016757 | molecular_function | glycosyltransferase activity |
| A | 0016763 | molecular_function | pentosyltransferase activity |
| A | 0019363 | biological_process | pyridine nucleotide biosynthetic process |
| A | 0034213 | biological_process | quinolinate catabolic process |
| B | 0004514 | molecular_function | nicotinate-nucleotide diphosphorylase (carboxylating) activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0009435 | biological_process | NAD+ biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016757 | molecular_function | glycosyltransferase activity |
| B | 0016763 | molecular_function | pentosyltransferase activity |
| B | 0019363 | biological_process | pyridine nucleotide biosynthetic process |
| B | 0034213 | biological_process | quinolinate catabolic process |
| C | 0004514 | molecular_function | nicotinate-nucleotide diphosphorylase (carboxylating) activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0009435 | biological_process | NAD+ biosynthetic process |
| C | 0016740 | molecular_function | transferase activity |
| C | 0016757 | molecular_function | glycosyltransferase activity |
| C | 0016763 | molecular_function | pentosyltransferase activity |
| C | 0019363 | biological_process | pyridine nucleotide biosynthetic process |
| C | 0034213 | biological_process | quinolinate catabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 C 2001 |
| Chain | Residue |
| C | LYS126 |
| C | ASN237 |
| C | GLY257 |
| C | ALA258 |
| C | HIS261 |
| C | HOH2043 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 2002 |
| Chain | Residue |
| B | ALA258 |
| B | HIS261 |
| B | HOH2003 |
| B | LYS126 |
| B | ASN237 |
| B | GLY257 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 2003 |
| Chain | Residue |
| A | LYS126 |
| A | ASN237 |
| A | VAL256 |
| A | GLY257 |
| A | ALA258 |
| A | HIS261 |
| A | HOH2062 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE NTM A 1001 |
| Chain | Residue |
| A | THR124 |
| A | ARG125 |
| A | HIS147 |
| A | ARG148 |
| A | MET156 |
| A | MET207 |
| A | GLU233 |
| A | HOH2004 |
| A | HOH2034 |
| B | ARG91 |
| site_id | AC5 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE NTM B 1002 |
| Chain | Residue |
| A | ARG91 |
| B | THR124 |
| B | ARG125 |
| B | HIS147 |
| B | ARG148 |
| B | MET156 |
| B | MET207 |
| B | GLU233 |
| B | HOH2006 |
| B | HOH2072 |
| B | HOH2078 |
| site_id | AC6 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE NTM C 1003 |
| Chain | Residue |
| C | ARG91 |
| C | THR124 |
| C | ARG125 |
| C | HIS147 |
| C | ARG148 |
| C | MET156 |
| C | LYS158 |
| C | MET207 |
| C | GLU233 |
| C | HOH2019 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 18 |
| Details | Binding site: {} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16419067","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1qpr |
| Chain | Residue | Details |
| A | ASP209 | |
| A | LYS126 | |
| A | GLU188 |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1qpr |
| Chain | Residue | Details |
| B | ASP209 | |
| B | LYS126 | |
| B | GLU188 |
| site_id | CSA3 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1qpr |
| Chain | Residue | Details |
| C | ASP209 | |
| C | LYS126 | |
| C | GLU188 |
| site_id | CSA4 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1qpr |
| Chain | Residue | Details |
| A | ARG91 |
| site_id | CSA5 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1qpr |
| Chain | Residue | Details |
| B | ARG91 |
| site_id | CSA6 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1qpr |
| Chain | Residue | Details |
| C | ARG91 |
