2B4V
Structural Basis for UTP Specificity of RNA Editing TUTases From Trypanosoma Brucei
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003723 | molecular_function | RNA binding |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0006397 | biological_process | mRNA processing |
| A | 0016779 | molecular_function | nucleotidyltransferase activity |
| A | 0031019 | cellular_component | mitochondrial mRNA editing complex |
| A | 0031123 | biological_process | RNA 3'-end processing |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0050265 | molecular_function | RNA uridylyltransferase activity |
| A | 0071076 | biological_process | RNA 3' uridylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE K A 1 |
| Chain | Residue |
| A | LEU285 |
| A | HIS286 |
| A | GLY288 |
| A | PRO289 |
| A | HOH516 |
| A | HOH696 |
| A | HOH701 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:16281058, ECO:0007744|PDB:2B51, ECO:0007744|PDB:2B56 |
| Chain | Residue | Details |
| A | LYS300 | |
| A | LYS304 | |
| A | SER318 | |
| A | SER85 | |
| A | SER96 | |
| A | ASN277 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:16281058 |
| Chain | Residue | Details |
| A | ASP99 | |
| A | ASP97 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:Q381M1 |
| Chain | Residue | Details |
| A | ARG210 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | SITE: Important for catalytic activity => ECO:0000305|PubMed:16281058 |
| Chain | Residue | Details |
| A | ASP267 |
