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2B4B

SSAT+COA+BE-3-3-3, K26R mutant

Functional Information from GO Data
ChainGOidnamespacecontents
A0001525biological_processangiogenesis
A0004145molecular_functiondiamine N-acetyltransferase activity
A0005515molecular_functionprotein binding
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0006596biological_processpolyamine biosynthetic process
A0008080molecular_functionN-acetyltransferase activity
A0009447biological_processputrescine catabolic process
A0016740molecular_functiontransferase activity
A0016746molecular_functionacyltransferase activity
A0016747molecular_functionacyltransferase activity, transferring groups other than amino-acyl groups
A0019809molecular_functionspermidine binding
A0032918biological_processspermidine acetylation
A0042127biological_processregulation of cell population proliferation
A0042802molecular_functionidentical protein binding
B0001525biological_processangiogenesis
B0004145molecular_functiondiamine N-acetyltransferase activity
B0005515molecular_functionprotein binding
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0006596biological_processpolyamine biosynthetic process
B0008080molecular_functionN-acetyltransferase activity
B0009447biological_processputrescine catabolic process
B0016740molecular_functiontransferase activity
B0016746molecular_functionacyltransferase activity
B0016747molecular_functionacyltransferase activity, transferring groups other than amino-acyl groups
B0019809molecular_functionspermidine binding
B0032918biological_processspermidine acetylation
B0042127biological_processregulation of cell population proliferation
B0042802molecular_functionidentical protein binding
Functional Information from PDB Data
site_idAC1
Number of Residues21
DetailsBINDING SITE FOR RESIDUE COA A 200
ChainResidue
ATYR27
AILE105
AGLY106
ASER107
ALEU128
AASN133
ASER136
APHE139
ATYR140
AARG142
AHOH203
AGLU62
AHOH218
BB33173
APHE94
APHE95
AVAL96
AARG101
AGLY102
APHE103
AGLY104

site_idAC2
Number of Residues15
DetailsBINDING SITE FOR RESIDUE COA B 172
ChainResidue
BPHE94
BPHE95
BVAL96
BARG101
BGLY102
BPHE103
BGLY104
BILE105
BGLY106
BSER107
BPHE139
BARG142
BARG143
BGLU171
BHOH197

site_idAC3
Number of Residues10
DetailsBINDING SITE FOR RESIDUE B33 B 173
ChainResidue
AGLU92
ALEU128
ACOA200
AHOH202
AHOH204
AHOH237
AHOH244
BASP82
BTRP84
BHOH211

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsACT_SITE: Proton donor => ECO:0000250|UniProtKB:P0A951
ChainResidueDetails
ATYR140
BTYR140

site_idSWS_FT_FI2
Number of Residues16
DetailsBINDING: BINDING => ECO:0000305|PubMed:17516632
ChainResidueDetails
ATYR27
BGLU92
BPHE94
BGLY102
BHIS126
BASN133
BTYR140
BGLU152
AGLU92
APHE94
AGLY102
AHIS126
AASN133
ATYR140
AGLU152
BTYR27

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PDB entries from 2025-06-11

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