2B3T
Structure of complex between E. coli translation termination factor RF1 and the PrmC methyltransferase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0006415 | biological_process | translational termination |
| A | 0006479 | biological_process | protein methylation |
| A | 0008168 | molecular_function | methyltransferase activity |
| A | 0008276 | molecular_function | protein methyltransferase activity |
| A | 0008757 | molecular_function | S-adenosylmethionine-dependent methyltransferase activity |
| A | 0010468 | biological_process | regulation of gene expression |
| A | 0016740 | molecular_function | transferase activity |
| A | 0018364 | biological_process | peptidyl-glutamine methylation |
| A | 0032259 | biological_process | methylation |
| A | 0036009 | molecular_function | protein-glutamine N-methyltransferase activity |
| A | 0102559 | molecular_function | peptide chain release factor N(5)-glutamine methyltransferase activity |
| B | 0003747 | molecular_function | translation release factor activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006412 | biological_process | translation |
| B | 0006415 | biological_process | translational termination |
| B | 0016149 | molecular_function | translation release factor activity, codon specific |
| B | 0043022 | molecular_function | ribosome binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE SAH A 300 |
| Chain | Residue |
| A | THR88 |
| A | ARG141 |
| A | MET142 |
| A | SER166 |
| A | ASP167 |
| A | TRP168 |
| A | ASN183 |
| A | ALA206 |
| A | LEU89 |
| A | PRO91 |
| A | GLY117 |
| A | THR118 |
| A | GLY119 |
| A | THR120 |
| A | ALA122 |
| A | ASP140 |
Functional Information from PROSITE/UniProt
| site_id | PS00092 |
| Number of Residues | 7 |
| Details | N6_MTASE N-6 Adenine-specific DNA methylases signature. IVSNPPY |
| Chain | Residue | Details |
| A | ILE180-TYR186 |
| site_id | PS00745 |
| Number of Residues | 17 |
| Details | RF_PROK_I Prokaryotic-type class I peptide chain release factors signature. RSsGaGGQHVNttdSAI |
| Chain | Residue | Details |
| B | ARG228-ILE244 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_02126","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"15223314","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15223314","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"16364916","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16364916","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15223314","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N5-methylglutamine","evidences":[{"source":"PubMed","id":"11118225","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11847124","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
