2B3J
Crystal Structure of Staphylococcus aureus tRNA Adenosine Deaminase, TadA, in Complex with RNA
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0002100 | biological_process | tRNA wobble adenosine to inosine editing |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0008033 | biological_process | tRNA processing |
| A | 0008251 | molecular_function | tRNA-specific adenosine deaminase activity |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0052717 | molecular_function | tRNA-specific adenosine-34 deaminase activity |
| B | 0002100 | biological_process | tRNA wobble adenosine to inosine editing |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0008033 | biological_process | tRNA processing |
| B | 0008251 | molecular_function | tRNA-specific adenosine deaminase activity |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0052717 | molecular_function | tRNA-specific adenosine-34 deaminase activity |
| C | 0002100 | biological_process | tRNA wobble adenosine to inosine editing |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0008033 | biological_process | tRNA processing |
| C | 0008251 | molecular_function | tRNA-specific adenosine deaminase activity |
| C | 0008270 | molecular_function | zinc ion binding |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0052717 | molecular_function | tRNA-specific adenosine-34 deaminase activity |
| D | 0002100 | biological_process | tRNA wobble adenosine to inosine editing |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0008033 | biological_process | tRNA processing |
| D | 0008251 | molecular_function | tRNA-specific adenosine deaminase activity |
| D | 0008270 | molecular_function | zinc ion binding |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0052717 | molecular_function | tRNA-specific adenosine-34 deaminase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 2001 |
| Chain | Residue |
| A | HIS53 |
| A | CYS83 |
| A | CYS86 |
| A | HOH2002 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 1001 |
| Chain | Residue |
| B | PHE122 |
| B | ASN123 |
| A | CYS83 |
| A | VAL84 |
| A | GLY107 |
| A | HOH2052 |
| A | HOH2059 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN B 2002 |
| Chain | Residue |
| B | HIS53 |
| B | GLU55 |
| B | CYS83 |
| B | CYS86 |
| B | HOH2003 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL B 1002 |
| Chain | Residue |
| A | PHE122 |
| A | ASN123 |
| B | CYS83 |
| B | VAL84 |
| B | GLY107 |
| B | HOH2041 |
| B | HOH2042 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN C 2003 |
| Chain | Residue |
| C | HIS53 |
| C | CYS83 |
| C | CYS86 |
| C | HOH2004 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL C 1004 |
| Chain | Residue |
| C | CYS83 |
| C | VAL84 |
| C | GLY107 |
| C | HOH2060 |
| D | PHE122 |
| D | ASN123 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN D 2004 |
| Chain | Residue |
| D | HIS53 |
| D | CYS83 |
| D | CYS86 |
| D | HOH2005 |
| site_id | AC8 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL D 1003 |
| Chain | Residue |
| C | MET92 |
| C | PHE122 |
| C | ASN123 |
| D | CYS83 |
| D | VAL84 |
| D | GLY107 |
| D | HOH2037 |
| D | HOH2053 |
| H | HOH50 |
Functional Information from PROSITE/UniProt
| site_id | PS00903 |
| Number of Residues | 38 |
| Details | CYT_DCMP_DEAMINASES_1 Cytidine and deoxycytidylate deaminases zinc-binding region signature. HAEhiAIeraakvlgswrlegctlyvtle...........PCvm......CagtI |
| Chain | Residue | Details |
| A | HIS53-ILE90 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 354 |
| Details | Domain: {"description":"CMP/dCMP-type deaminase","evidences":[{"source":"PROSITE-ProRule","id":"PRU01083","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"HAMAP-Rule","id":"MF_00972","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00972","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"16415880","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
