2B0T
Structure of Monomeric NADP Isocitrate dehydrogenase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004450 | molecular_function | isocitrate dehydrogenase (NADP+) activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006097 | biological_process | glyoxylate cycle |
| A | 0006099 | biological_process | tricarboxylic acid cycle |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 800 |
| Chain | Residue |
| A | ASP346 |
| A | ASP544 |
| A | ASP548 |
| A | HOH831 |
| A | HOH936 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 9 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:P16100 |
| Chain | Residue | Details |
| A | ASN83 | |
| A | SER85 | |
| A | SER130 | |
| A | ASN133 | |
| A | ARG137 | |
| A | ARG143 | |
| A | LYS253 | |
| A | TYR416 | |
| A | ARG543 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:16416443, ECO:0000269|PubMed:21931217, ECO:0007744|PDB:2B0T, ECO:0007744|PDB:3MBC |
| Chain | Residue | Details |
| A | ASP346 | |
| A | ASP544 | |
| A | ASP548 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 5 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:21931217, ECO:0007744|PDB:3MBC |
| Chain | Residue | Details |
| A | GLY580 | |
| A | HIS585 | |
| A | ARG596 | |
| A | ASP598 | |
| A | ARG645 |
