Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0003862 | molecular_function | 3-isopropylmalate dehydrogenase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0009098 | biological_process | L-leucine biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051287 | molecular_function | NAD binding |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0003862 | molecular_function | 3-isopropylmalate dehydrogenase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0009098 | biological_process | L-leucine biosynthetic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0051287 | molecular_function | NAD binding |
Functional Information from PROSITE/UniProt
| site_id | PS00470 |
| Number of Residues | 20 |
| Details | IDH_IMDH Isocitrate and isopropylmalate dehydrogenases signature. NMFGDIlSDeaSvit.GSLGM |
| Chain | Residue | Details |
| A | ASN242-MET261 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 16 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | GLY76 | |
| B | ARG96 | |
| B | ARG106 | |
| B | ARG134 | |
| B | ASP222 | |
| B | ASP246 | |
| B | ASP250 | |
| B | GLY280 | |
| A | ARG96 | |
| A | ARG106 | |
| A | ARG134 | |
| A | ASP222 | |
| A | ASP246 | |
| A | ASP250 | |
| A | GLY280 | |
| B | GLY76 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | SITE: Important for catalysis => ECO:0000250 |
| Chain | Residue | Details |
| A | TYR141 | |
| A | LYS190 | |
| B | TYR141 | |
| B | LYS190 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1a05 |
| Chain | Residue | Details |
| A | ASP222 | |
| A | LYS190 | |
| B | TYR141 | |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1a05 |
| Chain | Residue | Details |
| A | TYR141 | |
| B | ASP222 | |
| B | LYS190 | |
