2AX4
Crystal structure of the kinase domain of human 3'-phosphoadenosine 5'-phosphosulphate synthetase 2
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000103 | biological_process | sulfate assimilation |
| A | 0004020 | molecular_function | adenylylsulfate kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| B | 0000103 | biological_process | sulfate assimilation |
| B | 0004020 | molecular_function | adenylylsulfate kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| C | 0000103 | biological_process | sulfate assimilation |
| C | 0004020 | molecular_function | adenylylsulfate kinase activity |
| C | 0005524 | molecular_function | ATP binding |
| D | 0000103 | biological_process | sulfate assimilation |
| D | 0004020 | molecular_function | adenylylsulfate kinase activity |
| D | 0005524 | molecular_function | ATP binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE ADP A 800 |
| Chain | Residue |
| A | LEU60 |
| A | VAL170 |
| A | THR204 |
| A | SER207 |
| A | THR208 |
| A | VAL209 |
| A | CYS212 |
| A | HOH811 |
| A | GLY62 |
| A | ALA63 |
| A | GLY64 |
| A | LYS65 |
| A | THR66 |
| A | THR67 |
| A | ILE68 |
| A | ARG168 |
| site_id | AC2 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE ADP B 801 |
| Chain | Residue |
| B | GLY62 |
| B | ALA63 |
| B | GLY64 |
| B | LYS65 |
| B | THR66 |
| B | THR67 |
| B | ARG168 |
| B | VAL170 |
| B | THR204 |
| B | SER207 |
| B | THR208 |
| B | VAL209 |
| B | CYS212 |
| B | HOH807 |
| B | HOH818 |
| B | HOH858 |
| C | GLU222 |
| C | GLN223 |
| C | ASN224 |
| site_id | AC3 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE ADP C 802 |
| Chain | Residue |
| C | LEU60 |
| C | GLY62 |
| C | ALA63 |
| C | GLY64 |
| C | LYS65 |
| C | THR66 |
| C | THR67 |
| C | ILE68 |
| C | ARG168 |
| C | VAL170 |
| C | THR204 |
| C | SER207 |
| C | THR208 |
| C | VAL209 |
| C | CYS212 |
| C | HOH867 |
| site_id | AC4 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE ADP D 803 |
| Chain | Residue |
| A | GLU222 |
| A | GLN223 |
| A | ASN224 |
| D | GLY62 |
| D | ALA63 |
| D | GLY64 |
| D | LYS65 |
| D | THR66 |
| D | THR67 |
| D | ILE68 |
| D | ARG168 |
| D | VAL170 |
| D | THR204 |
| D | SER207 |
| D | THR208 |
| D | VAL209 |
| D | CYS212 |
| D | HOH818 |
| D | HOH829 |
| D | HOH835 |
| D | HOH848 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 24 |
| Details | Binding site: {"evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"SEP-2005","submissionDatabase":"PDB data bank","title":"Crystal structure of the kinase domain of PAPSS 2.","authoringGroup":["Structural genomics consortium (SGC)"]}},{"source":"PDB","id":"2AX4","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 40 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"O43252","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
