2AVD
Crystal Structure of Human Catechol-O-methyltransferase domain containing 1
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE SAM A 501 |
| Chain | Residue |
| A | SER84 |
| A | PRO162 |
| A | ALA163 |
| A | ASP185 |
| A | ALA186 |
| A | ASP187 |
| A | TYR194 |
| A | ARG212 |
| A | HOH502 |
| A | HOH510 |
| A | HOH524 |
| A | MET85 |
| A | HOH543 |
| A | HOH592 |
| A | HOH593 |
| A | HOH669 |
| A | HOH750 |
| A | MET86 |
| A | GLY110 |
| A | PHE112 |
| A | SER116 |
| A | CYS133 |
| A | GLU134 |
| A | VAL135 |
| site_id | AC2 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE SAM B 601 |
| Chain | Residue |
| A | GLU169 |
| B | SER84 |
| B | MET85 |
| B | MET86 |
| B | GLY110 |
| B | THR111 |
| B | PHE112 |
| B | TYR115 |
| B | SER116 |
| B | GLU134 |
| B | VAL135 |
| B | ALA163 |
| B | ASP185 |
| B | ALA186 |
| B | ASP187 |
| B | TYR194 |
| B | ARG212 |
| B | HOH605 |
| B | HOH612 |
| B | HOH630 |
| B | HOH653 |
| B | HOH776 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01019","evidenceCode":"ECO:0000255"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"MAR-2006","submissionDatabase":"PDB data bank","title":"The crystal structure of human catechol-O-methyltransferase domain containing 1 in complex with S-adenosyl-L-methionine.","authoringGroup":["Structural genomics consortium (SGC)"]}}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01019","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
