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2AUP

Residue F4 plays a key role in modulating oxygen affinity and cooperativity in Scapharca dimeric hemoglobin

Functional Information from GO Data
ChainGOidnamespacecontents
A0001666biological_processresponse to hypoxia
A0005344molecular_functionoxygen carrier activity
A0005737cellular_componentcytoplasm
A0015671biological_processoxygen transport
A0019825molecular_functionoxygen binding
A0020037molecular_functionheme binding
A0042802molecular_functionidentical protein binding
A0046872molecular_functionmetal ion binding
B0001666biological_processresponse to hypoxia
B0005344molecular_functionoxygen carrier activity
B0005737cellular_componentcytoplasm
B0015671biological_processoxygen transport
B0019825molecular_functionoxygen binding
B0020037molecular_functionheme binding
B0042802molecular_functionidentical protein binding
B0046872molecular_functionmetal ion binding
Functional Information from PDB Data
site_idAC1
Number of Residues16
DetailsBINDING SITE FOR RESIDUE HEM A 147
ChainResidue
ATYR50
AGLU110
APHE111
AHOH208
AHOH245
AHOH257
BLYS96
BASN100
APHE51
AARG53
ALEU54
AHIS69
ALEU77
AASN100
AHIS101
AARG104

site_idAC2
Number of Residues15
DetailsBINDING SITE FOR RESIDUE HEM B 147
ChainResidue
ALYS96
AASN100
BTYR50
BPHE51
BARG53
BHIS69
BLEU77
BASN100
BHIS101
BARG104
BILE106
BPHE111
BHOH218
BHOH229
BHOH263

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsBINDING: proximal binding residue
ChainResidueDetails
AHIS101
BHIS101

223166

PDB entries from 2024-07-31

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