Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004070 | molecular_function | aspartate carbamoyltransferase activity |
| A | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
| A | 0006520 | biological_process | amino acid metabolic process |
| A | 0016597 | molecular_function | amino acid binding |
| A | 0016743 | molecular_function | carboxyl- or carbamoyltransferase activity |
| B | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
| B | 0009347 | cellular_component | aspartate carbamoyltransferase complex |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 153 |
| Chain | Residue |
| B | CYS109 |
| B | CYS114 |
| B | CYS137 |
| B | CYS140 |
| site_id | CTA |
| Number of Residues | 13 |
| Details | RESIDUES BELIEVED TO BE INVOLVED IN THE BINDING OF SUBSTRATES |
| Chain | Residue |
| A | SER52 |
| A | TYR165 |
| A | ARG167 |
| A | LYS224 |
| A | TYR232 |
| A | ARG54 |
| A | THR55 |
| A | LYS83 |
| A | LYS84 |
| A | ARG105 |
| A | GLY128 |
| A | HIS134 |
| A | GLN137 |
| site_id | RGB |
| Number of Residues | 2 |
| Details | RESIDUES WHICH BIND EFFECTOR MOLECULES |
Functional Information from PROSITE/UniProt
| site_id | PS00097 |
| Number of Residues | 8 |
| Details | CARBAMOYLTRANSFERASE Aspartate and ornithine carbamoyltransferases signature. FfEaSTRT |
| Chain | Residue | Details |
| A | PHE48-THR55 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 7 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00001","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"3380787","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00001","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"3380787","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Binding site: {} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1at1 |
| Chain | Residue | Details |
| A | ARG54 | |
| A | HIS134 | |
| A | ARG105 | |
| A | THR55 | |
| site_id | MCSA1 |
| Number of Residues | 5 |
| Details | M-CSA 405 |
| Chain | Residue | Details |
| A | ARG54 | electrostatic stabiliser |
| A | THR55 | electrostatic stabiliser, increase electrophilicity |
| A | LYS84 | proton shuttle (general acid/base) |
| A | ARG105 | electrostatic stabiliser, increase electrophilicity |
| A | HIS134 | electrostatic stabiliser, increase electrophilicity |
