2ATB
Triple mutant 8D9D10V of scorpion toxin LQH-alpha-IT
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005576 | cellular_component | extracellular region |
| A | 0006952 | biological_process | defense response |
| A | 0008200 | molecular_function | ion channel inhibitor activity |
| A | 0017080 | molecular_function | sodium channel regulator activity |
| A | 0019871 | molecular_function | sodium channel inhibitor activity |
| A | 0035821 | biological_process | modulation of process of another organism |
| A | 0090729 | molecular_function | toxin activity |
| A | 0099106 | molecular_function | ion channel regulator activity |
| B | 0005576 | cellular_component | extracellular region |
| B | 0006952 | biological_process | defense response |
| B | 0008200 | molecular_function | ion channel inhibitor activity |
| B | 0017080 | molecular_function | sodium channel regulator activity |
| B | 0019871 | molecular_function | sodium channel inhibitor activity |
| B | 0035821 | biological_process | modulation of process of another organism |
| B | 0090729 | molecular_function | toxin activity |
| B | 0099106 | molecular_function | ion channel regulator activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE NO3 A 66 |
| Chain | Residue |
| A | CYS13 |
| A | VAL14 |
| A | ARG59 |
| A | CYS64 |
| A | HOH73 |
| B | TYR43 |
| B | HOH688 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B 301 |
| Chain | Residue |
| B | CYS64 |
| B | VAL14 |
| B | ARG59 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE NO3 B 401 |
| Chain | Residue |
| A | PRO53 |
| A | ASN55 |
| A | HOH76 |
| A | HOH169 |
| B | ARG19 |
| B | ALA21 |
| B | HOH610 |
| B | HOH656 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO B 501 |
| Chain | Residue |
| B | TYR6 |
| B | GLN38 |
| B | GLY41 |
| B | LYS42 |
| B | TYR43 |
| B | GLY44 |
| B | ALA46 |
| B | EDO601 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO B 601 |
| Chain | Residue |
| B | TYR6 |
| B | LYS42 |
| B | VAL60 |
| B | PRO61 |
| B | EDO501 |
| B | HOH660 |
| B | HOH663 |
