2AT8

0.96 A Crystal Structure Of Nitrophorin 4 From Rhodnius Prolixus Containing Fe(III) 2,4 Dimethyl Deuteroporphyrin IX Complexed With Nitric Oxide at pH 5.6

Functional Information from GO Data

Chain	GOid	namespace	contents
X	0005576	cellular_component	extracellular region
X	0016491	molecular_function	oxidoreductase activity
X	0042311	biological_process	vasodilation
X	0046872	molecular_function	metal ion binding
X	0051381	molecular_function	histamine binding
X	0070026	molecular_function	nitric oxide binding
X	0097746	biological_process	blood vessel diameter maintenance

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PO4 X 187

Chain	Residue
X	THR10
X	GLY11
X	PRO37
X	LYS38
X	ARG39
X	LYS63
X	HOH410
X	HOH417

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site_id	AC2
Number of Residues	18
Details	BINDING SITE FOR RESIDUE FDD X 185

Chain	Residue
X	TYR40
X	LEU57
X	HIS59
X	PHE68
X	ASP70
X	PHE86
X	LYS88
X	TYR105
X	ILE119
X	LEU123
X	LYS125
X	LYS128
X	LEU130
X	LEU133
X	NO186
X	HOH279
X	HOH351
X	VAL36

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site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE NO X 186

Chain	Residue
X	LEU123
X	LEU130
X	LEU133
X	FDD185

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Binding site: {"description":"proximal binding residue","evidences":[{"source":"PubMed","id":"10876239","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11560480","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"14673714","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16171383","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20524697","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22334402","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22976968","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23474537","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9782054","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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