2ASQ

Solution Structure of SUMO-1 in Complex with a SUMO-binding Motif (SBM)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000122	biological_process	negative regulation of transcription by RNA polymerase II
A	0001741	cellular_component	XY body
A	0003723	molecular_function	RNA binding
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005643	cellular_component	nuclear pore
A	0005654	cellular_component	nucleoplasm
A	0005730	cellular_component	nucleolus
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0005886	cellular_component	plasma membrane
A	0006281	biological_process	DNA repair
A	0015459	molecular_function	potassium channel regulator activity
A	0016604	cellular_component	nuclear body
A	0016605	cellular_component	PML body
A	0016607	cellular_component	nuclear speck
A	0016925	biological_process	protein sumoylation
A	0019899	molecular_function	enzyme binding
A	0031334	biological_process	positive regulation of protein-containing complex assembly
A	0031386	molecular_function	protein tag activity
A	0031625	molecular_function	ubiquitin protein ligase binding
A	0031647	biological_process	regulation of protein stability
A	0031965	cellular_component	nuclear membrane
A	0032436	biological_process	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
A	0034605	biological_process	cellular response to heat
A	0042308	biological_process	negative regulation of protein import into nucleus
A	0044388	molecular_function	small protein activating enzyme binding
A	0044389	molecular_function	ubiquitin-like protein ligase binding
A	0045759	biological_process	negative regulation of action potential
A	0045892	biological_process	negative regulation of DNA-templated transcription
A	0050821	biological_process	protein stabilization
A	0060021	biological_process	roof of mouth development
A	0060633	biological_process	negative regulation of transcription initiation by RNA polymerase II
A	0071276	biological_process	cellular response to cadmium ion
A	0086004	biological_process	regulation of cardiac muscle cell contraction
A	0097165	cellular_component	nuclear stress granule
A	0098978	cellular_component	glutamatergic synapse
A	0099523	cellular_component	presynaptic cytosol
A	0099524	cellular_component	postsynaptic cytosol
A	0141109	molecular_function	transporter activator activity
A	1903169	biological_process	regulation of calcium ion transmembrane transport
A	1990381	molecular_function	ubiquitin-specific protease binding

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	Region: {"description":"(Microbial infection) Interaction with Tula hantavirus","evidences":[{"source":"PubMed","id":"12606074","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	1
Details	Site: {"description":"Interaction with PIAS2"}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	4
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins)","evidences":[{"source":"PubMed","id":"27068747","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)"}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	1
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"25755297","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	6
Details	Region: {"description":"SUMO1-binding"}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	3
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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