2ASC

Scorpion toxin LQH-alpha-IT

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005576	cellular_component	extracellular region
A	0006952	biological_process	defense response
A	0008200	molecular_function	ion channel inhibitor activity
A	0017080	molecular_function	sodium channel regulator activity
A	0019871	molecular_function	sodium channel inhibitor activity
A	0035821	biological_process	modulation of process of another organism
A	0090729	molecular_function	toxin activity
A	0099106	molecular_function	ion channel regulator activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	BINDING SITE FOR RESIDUE DR8 A 3001

Chain	Residue
A	TYR36
A	TYR36
A	TYR36
A	TYR50
A	TYR50
A	TYR50
A	DR01002
A	DR01002
A	DR01002

---

site_id	AC2
Number of Residues	10
Details	BINDING SITE FOR RESIDUE DR0 A 1002

Chain	Residue
A	ASP20
A	TYR36
A	CYS37
A	TRP39
A	CL1005
A	EDO2005
A	DR83001
A	DR83001
A	DR83001
A	HOH9007

---

site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL A 1005

Chain	Residue
A	TRP39
A	DR01002
A	HOH9007

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL A 1006

Chain	Residue
A	VAL14
A	ARG59
A	CYS64
A	EOH5001

---

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL A 1007

Chain	Residue
A	SER34
A	GLY35
A	TYR50
A	TYR50
A	EDO2004

---

site_id	AC6
Number of Residues	11
Details	BINDING SITE FOR RESIDUE NO3 A 1001

Chain	Residue
A	ASP4
A	SER33
A	TYR50
A	TYR50
A	TYR50
A	HOH9030
A	HOH9030
A	HOH9030
A	HOH9039
A	HOH9039
A	HOH9039

---

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE K A 2001

Chain	Residue
A	GLU16
A	GLU16
A	TYR22
A	TYR22

---

site_id	AC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO A 2003

Chain	Residue
A	TYR6
A	ASP20
A	ALA21
A	ASN24
A	EDO2004
A	HOH9003
A	HOH9014

---

site_id	AC9
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EDO A 2004

Chain	Residue
A	ASP20
A	ASN24
A	GLY35
A	TYR36
A	TYR36
A	TRP48
A	CL1007
A	EDO2003

---

site_id	BC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO A 2005

Chain	Residue
A	PHE18
A	ARG19
A	TRP39
A	ALA40
A	DR01002
A	HOH9008

---

site_id	BC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 2101

Chain	Residue
A	PHE18
A	TRP39
A	ALA40
A	ASN45

---

site_id	BC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 2201

Chain	Residue
A	ASN30
A	ASN55
A	VAL56
A	HOH9068

---

site_id	BC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MOH A 4001

Chain	Residue
A	ALA8
A	TYR15

---

site_id	BC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EOH A 5001

Chain	Residue
A	VAL14
A	GLU16
A	ARG19
A	TYR43
A	CL1006
A	HOH9023

---

site_id	BC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EOH A 6001

Chain	Residue
A	LYS42
A	TYR43
A	ARG59
A	VAL60
A	PRO61
A	HOH9044

---

site_id	BC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MOH A 7001

Chain	Residue
A	ASP54
A	PRO57

---

site_id	BC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EOH A 8001

Chain	Residue
A	THR28
A	GLY31
A	ASP54
A	ASN55
A	HOH9060
A	HOH9063
A	HOH9066

---

site_id	BC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MOH A 9001

Chain	Residue
A	GLU25
A	HOH9031
A	HOH9036
A	ARG19

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