2ART
Crystal structure of lipoate-protein ligase A bound with lipoyl-AMP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0005515 | molecular_function | protein binding |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0009249 | biological_process | protein lipoylation |
| A | 0016874 | molecular_function | ligase activity |
| A | 0016979 | molecular_function | lipoate-protein ligase activity |
| A | 0017118 | molecular_function | lipoyltransferase activity |
| A | 0031405 | molecular_function | lipoic acid binding |
| A | 0032991 | cellular_component | protein-containing complex |
| A | 0036211 | biological_process | protein modification process |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 1301 |
| Chain | Residue |
| A | THR137 |
| A | ASP138 |
| A | GLY148 |
| A | ALA149 |
| A | LPA301 |
| A | AMP302 |
| site_id | AC2 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE LPA A 301 |
| Chain | Residue |
| A | VAL79 |
| A | HIS81 |
| A | LYS145 |
| A | GLY148 |
| A | ALA149 |
| A | HIS161 |
| A | ALA163 |
| A | AMP302 |
| A | MG1301 |
| A | ILE46 |
| A | ARG72 |
| A | GLY77 |
| site_id | AC3 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE AMP A 302 |
| Chain | Residue |
| A | GLY77 |
| A | VAL79 |
| A | TYR80 |
| A | ASP85 |
| A | PRO132 |
| A | LYS135 |
| A | ASP138 |
| A | LYS145 |
| A | GLY148 |
| A | ALA163 |
| A | LEU165 |
| A | LEU173 |
| A | LEU177 |
| A | LPA301 |
| A | MG1301 |
| A | HOH1308 |
| A | HOH1335 |
| A | HOH1377 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16141198","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2ARU","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 7 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16141198","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2ART","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ARU","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16141198","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16384580","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2ARS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ART","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ARU","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
