2AQ2
Crystal structure of T-cell receptor V beta domain variant complexed with superantigen SEC3 mutant
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0002250 | biological_process | adaptive immune response |
| A | 0002376 | biological_process | immune system process |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0007166 | biological_process | cell surface receptor signaling pathway |
| A | 0042101 | cellular_component | T cell receptor complex |
| B | 0005576 | cellular_component | extracellular region |
| B | 0035821 | biological_process | modulation of process of another organism |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0090729 | molecular_function | toxin activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ZN B 1001 |
| Chain | Residue |
| B | ASP83 |
| B | HIS116 |
| B | HIS120 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE NA B 1002 |
| Chain | Residue |
| A | GLU1 |
| B | PHE174 |
| B | ASN175 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE NA B 1003 |
| Chain | Residue |
| B | LYS25 |
| B | PHE174 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA B 1004 |
| Chain | Residue |
| B | THR114 |
| B | LYS115 |
| B | HOH1150 |
| B | TYR77 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 500 |
| Chain | Residue |
| A | TYR33 |
| A | HOH174 |
| B | HIS47 |
| B | ASN70 |
| B | GLU71 |
| site_id | AC6 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE SO4 B 501 |
| Chain | Residue |
| A | HOH131 |
| B | TYR26 |
| B | HIS31 |
| B | ASP55 |
| B | ASN60 |
| B | ASN88 |
| B | TYR90 |
| B | HOH1050 |
| B | HOH1086 |
| B | HOH1088 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 502 |
| Chain | Residue |
| B | LYS75 |
| B | ARG138 |
| B | HOH1038 |
| B | HOH1142 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 503 |
| Chain | Residue |
| B | LYS75 |
| B | LYS78 |
| B | ARG138 |
| B | HOH1059 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 504 |
| Chain | Residue |
| B | GLY203 |
| B | ASP204 |
| B | LYS205 |
| B | HOH1151 |
Functional Information from PROSITE/UniProt
| site_id | PS00277 |
| Number of Residues | 10 |
| Details | STAPH_STREP_TOXIN_1 Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin signature 1. YGGITKHegN |
| Chain | Residue | Details |
| B | TYR110-ASN119 |
| site_id | PS00278 |
| Number of Residues | 24 |
| Details | STAPH_STREP_TOXIN_2 Staphyloccocal enterotoxin/Streptococcal pyrogenic exotoxin signature 2. KksVtaqeLDikaRnfLinkknLY |
| Chain | Residue | Details |
| B | LYS149-TYR172 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"20836565","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"JAN-2008","submissionDatabase":"PDB data bank","title":"Manipulating the coupled folding and binding process drives affinity maturation in a protein-protein complex.","authors":["Cho S.","Swaminathan C.P.","Kerzic M.C.","Guan R.","Yang J.","Kieke M.C.","Andersen P.S.","Krantz D.M.","Mariuzza R.A.","Eric S.J."]}},{"source":"PDB","id":"3BVG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BVM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BVZ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
