2AP9

Crystal structure of acetylglutamate kinase from Mycobacterium tuberculosis CDC1551

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003991	molecular_function	acetylglutamate kinase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005886	cellular_component	plasma membrane
A	0006526	biological_process	arginine biosynthetic process
A	0009274	cellular_component	peptidoglycan-based cell wall
A	0016301	molecular_function	kinase activity
A	0016310	biological_process	phosphorylation
A	0042450	biological_process	arginine biosynthetic process via ornithine
B	0003991	molecular_function	acetylglutamate kinase activity
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0005886	cellular_component	plasma membrane
B	0006526	biological_process	arginine biosynthetic process
B	0009274	cellular_component	peptidoglycan-based cell wall
B	0016301	molecular_function	kinase activity
B	0016310	biological_process	phosphorylation
B	0042450	biological_process	arginine biosynthetic process via ornithine
C	0003991	molecular_function	acetylglutamate kinase activity
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0005886	cellular_component	plasma membrane
C	0006526	biological_process	arginine biosynthetic process
C	0009274	cellular_component	peptidoglycan-based cell wall
C	0016301	molecular_function	kinase activity
C	0016310	biological_process	phosphorylation
C	0042450	biological_process	arginine biosynthetic process via ornithine
D	0003991	molecular_function	acetylglutamate kinase activity
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0005886	cellular_component	plasma membrane
D	0006526	biological_process	arginine biosynthetic process
D	0009274	cellular_component	peptidoglycan-based cell wall
D	0016301	molecular_function	kinase activity
D	0016310	biological_process	phosphorylation
D	0042450	biological_process	arginine biosynthetic process via ornithine
E	0003991	molecular_function	acetylglutamate kinase activity
E	0005524	molecular_function	ATP binding
E	0005737	cellular_component	cytoplasm
E	0005886	cellular_component	plasma membrane
E	0006526	biological_process	arginine biosynthetic process
E	0009274	cellular_component	peptidoglycan-based cell wall
E	0016301	molecular_function	kinase activity
E	0016310	biological_process	phosphorylation
E	0042450	biological_process	arginine biosynthetic process via ornithine
F	0003991	molecular_function	acetylglutamate kinase activity
F	0005524	molecular_function	ATP binding
F	0005737	cellular_component	cytoplasm
F	0005886	cellular_component	plasma membrane
F	0006526	biological_process	arginine biosynthetic process
F	0009274	cellular_component	peptidoglycan-based cell wall
F	0016301	molecular_function	kinase activity
F	0016310	biological_process	phosphorylation
F	0042450	biological_process	arginine biosynthetic process via ornithine

Functional Information from PDB Data

site_id	AC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG D 1001

Chain	Residue
D	GLU282

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site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG A 1002

Chain	Residue
A	ASP235
A	HIS301
A	HIS304

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site_id	AC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE NI A 1003

Chain	Residue
A	HIS303

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	18
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00082

Chain	Residue	Details
A	GLY71
D	GLY71
D	ARG93
D	ASN192
E	GLY71
E	ARG93
E	ASN192
F	GLY71
F	ARG93
F	ASN192
A	ARG93
A	ASN192
B	GLY71
B	ARG93
B	ASN192
C	GLY71
C	ARG93
C	ASN192

---

site_id	SWS_FT_FI2
Number of Residues	12
Details	SITE: Transition state stabilizer => ECO:0000255|HAMAP-Rule:MF_00082

Chain	Residue	Details
A	LYS36
E	LYS253
F	LYS36
F	LYS253
A	LYS253
B	LYS36
B	LYS253
C	LYS36
C	LYS253
D	LYS36
D	LYS253
E	LYS36

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	4
Details	Annotated By Reference To The Literature 1oh9

Chain	Residue	Details
A	GLY39
A	GLY72
A	LYS253
A	LYS36

---

site_id	CSA2
Number of Residues	4
Details	Annotated By Reference To The Literature 1oh9

Chain	Residue	Details
B	GLY39
B	GLY72
B	LYS253
B	LYS36

---

site_id	CSA3
Number of Residues	4
Details	Annotated By Reference To The Literature 1oh9

Chain	Residue	Details
C	GLY39
C	GLY72
C	LYS253
C	LYS36

---

site_id	CSA4
Number of Residues	4
Details	Annotated By Reference To The Literature 1oh9

Chain	Residue	Details
D	GLY39
D	GLY72
D	LYS253
D	LYS36

---

site_id	CSA5
Number of Residues	4
Details	Annotated By Reference To The Literature 1oh9

Chain	Residue	Details
E	GLY39
E	GLY72
E	LYS253
E	LYS36

---

site_id	CSA6
Number of Residues	4
Details	Annotated By Reference To The Literature 1oh9

Chain	Residue	Details
F	GLY39
F	GLY72
F	LYS253
F	LYS36

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