Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA A 701 |
| Chain | Residue |
| A | ASP60 |
| A | HOH1066 |
| A | HOH1155 |
| A | HOH1162 |
| A | HOH1168 |
| A | HOH1193 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 702 |
| Chain | Residue |
| A | THR74 |
| A | ASN88 |
| B | ARG141 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL B 703 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACY B 801 |
| Chain | Residue |
| B | ASN188 |
| B | HOH1068 |
| B | HOH1187 |
| B | HOH1249 |
| C | ARG301 |
| site_id | AC5 |
| Number of Residues | 61 |
| Details | BINDING SITE FOR CHAIN C OF PEPTIDE INHIBITOR |
| Chain | Residue |
| A | TRP6 |
| A | ARG8 |
| A | LEU23 |
| A | ASP25 |
| A | GLY27 |
| A | ALA28 |
| A | ASP29 |
| A | ASP30 |
| A | VAL32 |
| A | LYS45 |
| A | MET46 |
| A | ILE47 |
| A | GLY48 |
| A | GLY49 |
| A | ILE50 |
| A | PRO81 |
| A | ILE84 |
| A | HOH1199 |
| B | ARG108 |
| B | LEU123 |
| B | ASP125 |
| B | GLY127 |
| B | ALA128 |
| B | ASP129 |
| B | ASP130 |
| B | LYS145 |
| B | MET146 |
| B | ILE147 |
| B | GLY148 |
| B | GLY149 |
| B | ILE150 |
| B | GLN161 |
| B | ILE172 |
| B | ALA182 |
| B | ILE184 |
| B | ARG187 |
| B | ACY801 |
| B | HOH1006 |
| B | HOH1013 |
| B | HOH1096 |
| B | HOH1172 |
| B | HOH1191 |
| B | HOH1246 |
| C | HOH1010 |
| C | HOH1021 |
| C | HOH1024 |
| C | HOH1079 |
| C | HOH1117 |
| C | HOH1128 |
| C | HOH1131 |
| C | HOH1134 |
| C | HOH1150 |
| C | HOH1167 |
| C | HOH1176 |
| C | HOH1205 |
| C | HOH1207 |
| C | HOH1229 |
| C | HOH1253 |
| C | HOH1262 |
| C | HOH1294 |
| C | HOH1298 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADDTVI |
| Chain | Residue | Details |
| A | ALA22-ILE33 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | SITE: Cleavage; by viral protease => ECO:0000250 |
| Chain | Residue | Details |
| A | ILE64 | |
| B | ILE164 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphotyrosine; by host => ECO:0000250 |
| Chain | Residue | Details |
| A | ILE64 | |
| B | ILE164 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1a30 |
| Chain | Residue | Details |
| A | ASP25 | |
| A | THR26 | |
| B | THR126 | |
| B | ASP125 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a30 |
| Chain | Residue | Details |
| A | ASP25 | |
| B | ASP125 | |
