2ANV
crystal structure of P22 lysozyme mutant L86M
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003796 | molecular_function | lysozyme activity |
| A | 0009253 | biological_process | peptidoglycan catabolic process |
| A | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| A | 0016998 | biological_process | cell wall macromolecule catabolic process |
| A | 0030430 | cellular_component | host cell cytoplasm |
| A | 0031640 | biological_process | killing of cells of another organism |
| A | 0042742 | biological_process | defense response to bacterium |
| A | 0044659 | biological_process | viral release from host cell by cytolysis |
| B | 0003796 | molecular_function | lysozyme activity |
| B | 0009253 | biological_process | peptidoglycan catabolic process |
| B | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| B | 0016998 | biological_process | cell wall macromolecule catabolic process |
| B | 0030430 | cellular_component | host cell cytoplasm |
| B | 0031640 | biological_process | killing of cells of another organism |
| B | 0042742 | biological_process | defense response to bacterium |
| B | 0044659 | biological_process | viral release from host cell by cytolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 601 |
| Chain | Residue |
| A | PRO135 |
| A | ARG139 |
| A | HOH3006 |
| A | HOH3129 |
| A | HOH3160 |
| A | HOH3528 |
| B | HOH3439 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 602 |
| Chain | Residue |
| B | HOH3022 |
| B | HOH3137 |
| B | HOH3404 |
| B | PRO135 |
| B | ARG139 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 A 603 |
| Chain | Residue |
| A | THR50 |
| A | LYS111 |
| A | TYR113 |
| A | GLN114 |
| A | HOH3035 |
| A | HOH3041 |
| A | HOH3277 |
| A | HOH3353 |
| A | HOH4290 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 604 |
| Chain | Residue |
| A | ARG19 |
| A | LEU20 |
| A | LYS21 |
| A | HOH3072 |
| B | HOH3100 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 605 |
| Chain | Residue |
| A | ARG11 |
| A | HOH3140 |
| A | HOH3187 |
| A | HOH3212 |
| B | THR52 |
| B | LYS55 |
| B | CL2993 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 606 |
| Chain | Residue |
| A | ARG27 |
| B | TYR23 |
| B | ASP25 |
| B | SER26 |
| B | HOH3210 |
| B | HOH3227 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE MG A 2831 |
| Chain | Residue |
| A | ASP69 |
| A | HOH4401 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SM B 2901 |
| Chain | Residue |
| A | ASP129 |
| A | ASP131 |
| B | ASP129 |
| B | ASP131 |
| B | HOH3014 |
| B | HOH3048 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SM A 2902 |
| Chain | Residue |
| A | GLU62 |
| A | GLN65 |
| A | HOH3807 |
| B | GLN65 |
| B | HOH3195 |
| B | HOH3225 |
| B | HOH3292 |
| site_id | BC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SM A 2904 |
| Chain | Residue |
| A | GLU54 |
| A | GLU54 |
| A | GLU58 |
| A | GLU58 |
| A | HOH4158 |
| A | HOH4158 |
| site_id | BC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE IOD B 2981 |
| Chain | Residue |
| B | SER24 |
| B | SER47 |
| site_id | BC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE IOD B 2982 |
| Chain | Residue |
| A | THR10 |
| B | HOH3314 |
| site_id | BC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE IOD A 2983 |
| Chain | Residue |
| B | SER6 |
| B | LYS61 |
| site_id | BC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE IOD B 2984 |
| Chain | Residue |
| A | LYS111 |
| A | HOH4281 |
| B | LYS111 |
| site_id | BC6 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE IOD A 2985 |
| Chain | Residue |
| A | HOH3098 |
| site_id | BC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE IOD B 2986 |
| Chain | Residue |
| A | SER26 |
| B | GLY127 |
| B | HOH3110 |
| site_id | BC8 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE CL A 2991 |
| Chain | Residue |
| A | LYS39 |
| A | ASP41 |
| A | LYS55 |
| A | LEU59 |
| A | HOH3224 |
| B | MET1 |
| B | SER72 |
| B | HOH3027 |
| B | HOH3053 |
| site_id | BC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL B 2993 |
| Chain | Residue |
| A | SO4605 |
| B | THR52 |
| B | LYS55 |
| B | HOH3506 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: Proton donor/acceptor => ECO:0000255|HAMAP-Rule:MF_04110 |
| Chain | Residue | Details |
| A | GLU16 | |
| A | ASP25 | |
| B | GLU16 | |
| B | ASP25 |
