2AM4
Crystal Structure of N-Acetylglucosaminyltransferase I in Complex with UDP-2-deoxy-2-fluoro-glucose
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN A 448 |
| Chain | Residue |
| A | ASP213 |
| A | U2F449 |
| A | HOH463 |
| A | HOH467 |
| A | HOH468 |
| site_id | AC2 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR RESIDUE U2F A 449 |
| Chain | Residue |
| A | ASP144 |
| A | CYS145 |
| A | TYR184 |
| A | LYS186 |
| A | ILE187 |
| A | HIS190 |
| A | GLU211 |
| A | ASP212 |
| A | ASP213 |
| A | LEU269 |
| A | ASP291 |
| A | GLY320 |
| A | VAL321 |
| A | SER322 |
| A | MN448 |
| A | HOH467 |
| A | HOH470 |
| A | HOH478 |
| A | HOH481 |
| A | HOH483 |
| A | HOH526 |
| A | HOH591 |
| A | HOH644 |
| A | HOH654 |
| A | HOH705 |
| A | ILE113 |
| A | ALA114 |
| A | CYS115 |
| A | ARG117 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 450 |
| Chain | Residue |
| A | ARG131 |
| A | ILE139 |
| A | SER159 |
| A | ALA160 |
| A | VAL161 |
| A | THR162 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 454 |
| Chain | Residue |
| A | PRO235 |
| A | LEU237 |
| A | ARG303 |
| A | HOH465 |
| A | HOH548 |
| A | HOH708 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"11032794","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16769084","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1FOA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2AM3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2AM4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2AM5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2APC","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"11032794","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1FOA","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"11032794","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16769084","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1FOA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2AM3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2AM4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2AM5","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1foa |
| Chain | Residue | Details |
| A | ASP291 |
| site_id | MCSA1 |
| Number of Residues | 2 |
| Details | M-CSA 770 |
| Chain | Residue | Details |
| A | ASP213 | metal ligand |
| A | ASP291 | activator, proton acceptor, proton donor |
