2AK1

Crystal Structure of Cocaine catalytic Antibody 7A1 Fab' in Complex with benzoic acid

Functional Information from GO Data

Chain	GOid	namespace	contents
L	0002250	biological_process	adaptive immune response
L	0005515	molecular_function	protein binding
L	0005576	cellular_component	extracellular region
L	0005886	cellular_component	plasma membrane
L	0030183	biological_process	B cell differentiation
L	0042105	cellular_component	alpha-beta T cell receptor complex
L	0071735	cellular_component	IgG immunoglobulin complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN L 501

Chain	Residue
H	HIS172
L	ASN138
L	ASP167
L	HOH504
L	HOH637

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site_id	AC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE ZN H 502

Chain	Residue
H	GLU1

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site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN L 503

Chain	Residue
L	HOH623
H	GLN204
L	GLU185
L	HIS189

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site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE ZN H 504

Chain	Residue
H	ASP72
H	SER74

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site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE BEZ H 401

Chain	Residue
H	ASN32
H	ALA34
H	TYR97
L	LYS107

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Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH

Chain	Residue	Details
L	TYR192-HIS198

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	97
Details	Domain: {"description":"Ig-like","evidences":[{"source":"PROSITE-ProRule","id":"PRU00114","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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