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2AJZ

Crystal Structure of Cocaine catalytic Antibody 7A1 Fab' in Complex with ecgonine methyl ester

Functional Information from GO Data
ChainGOidnamespacecontents
A0002250biological_processadaptive immune response
A0005515molecular_functionprotein binding
A0005576cellular_componentextracellular region
A0005886cellular_componentplasma membrane
A0030183biological_processB cell differentiation
A0042105cellular_componentalpha-beta T cell receptor complex
A0071735cellular_componentIgG immunoglobulin complex
L0002250biological_processadaptive immune response
L0005515molecular_functionprotein binding
L0005576cellular_componentextracellular region
L0005886cellular_componentplasma membrane
L0030183biological_processB cell differentiation
L0042105cellular_componentalpha-beta T cell receptor complex
L0071735cellular_componentIgG immunoglobulin complex
Functional Information from PDB Data
site_idAC1
Number of Residues6
DetailsBINDING SITE FOR RESIDUE ECG L 301
ChainResidue
HTYR97
LTYR27
LVAL92
LGLU93
LTYR94
LPHE96

site_idAC2
Number of Residues5
DetailsBINDING SITE FOR RESIDUE ECG A 302
ChainResidue
APHE96
BTYR97
ATYR32
AVAL92
ATYR94

Functional Information from PROSITE/UniProt
site_idPS00290
Number of Residues7
DetailsIG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH
ChainResidueDetails
LTYR192-HIS198

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues194
DetailsDomain: {"description":"Ig-like","evidences":[{"source":"PROSITE-ProRule","id":"PRU00114","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

245663

PDB entries from 2025-12-03

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