2AJY

Crystal Structure of Cocaine catalytic Antibody 7A1 Fab' in Complex with ecgonine methyl ester and benzoic acid

Functional Information from GO Data

Chain	GOid	namespace	contents
L	0005576	cellular_component	extracellular region
L	0005886	cellular_component	plasma membrane
L	0030183	biological_process	B cell differentiation

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN L 301

Chain	Residue
H	HIS172
L	ASN138
L	ASP167
L	HOH333
L	HOH393

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site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE ZN L 302

Chain	Residue
L	ASP1
L	HOH377

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site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ZN L 303

Chain	Residue
L	ARG155
L	GLU185
L	HIS189
L	HOH389
H	THR199
H	GLN204

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site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE ZN H 304

Chain	Residue
H	ASP72
H	SER74

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site_id	AC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE ZN H 305

Chain	Residue
H	GLU1

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site_id	AC6
Number of Residues	8
Details	BINDING SITE FOR RESIDUE ECG L 304

Chain	Residue
H	TYR97
L	TYR27
L	TYR32
L	PHE91
L	VAL92
L	TYR94
L	PHE96
L	HOH346

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site_id	AC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE BEZ H 306

Chain	Residue
H	ASN32
H	ARG52

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Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH

Chain	Residue	Details
L	TYR192-HIS198

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