2AJS

Crystal structure of cocaine catalytic antibody 7A1 Fab' in complex with heptaethylene glycol

Functional Information from GO Data

Chain	GOid	namespace	contents
L	0002250	biological_process	adaptive immune response
L	0005576	cellular_component	extracellular region
L	0005886	cellular_component	plasma membrane
L	0030183	biological_process	B cell differentiation
L	0042105	cellular_component	alpha-beta T cell receptor complex
L	0071735	cellular_component	IgG immunoglobulin complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 H 601

Chain	Residue
H	THR31
H	ASN32
H	HOH770
H	HOH784
H	HOH807
L	LYS149

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site_id	AC2
Number of Residues	11
Details	BINDING SITE FOR RESIDUE P33 H 701

Chain	Residue
H	TYR50
H	TYR97
L	TYR27
L	TYR32
L	PHE91
L	VAL92
L	PHE96
L	HOH753
H	ALA34
H	THR35
H	TRP47

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site_id	AC3
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GOL L 501

Chain	Residue
H	PRO175
H	THR186
H	LEU187
H	THR188
L	LEU160
L	SER162
L	SER176
L	THR178
L	HOH699

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site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL L 502

Chain	Residue
L	SER59
L	ARG61
L	LYS79
L	HOH634
L	HOH676

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site_id	AC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL L 503

Chain	Residue
H	ASP72
H	THR73
H	SER74
L	LYS199
L	SER201
L	THR202
L	HOH601

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site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL L 504

Chain	Residue
L	ARG27
L	SER27
L	LYS27
L	HOH554
L	HOH631
L	HOH678

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Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH

Chain	Residue	Details
L	TYR192-HIS198

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	97
Details	Domain: {"description":"Ig-like","evidences":[{"source":"PROSITE-ProRule","id":"PRU00114","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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