2AJI

Crystal structure of the editing domain of E. coli leucyl-tRNA synthetase complexes with isoleucine

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0002161	molecular_function	aminoacyl-tRNA deacylase activity
A	0004823	molecular_function	leucine-tRNA ligase activity
A	0005524	molecular_function	ATP binding
A	0006418	biological_process	tRNA aminoacylation for protein translation
A	0006429	biological_process	leucyl-tRNA aminoacylation
B	0000166	molecular_function	nucleotide binding
B	0002161	molecular_function	aminoacyl-tRNA deacylase activity
B	0004823	molecular_function	leucine-tRNA ligase activity
B	0005524	molecular_function	ATP binding
B	0006418	biological_process	tRNA aminoacylation for protein translation
B	0006429	biological_process	leucyl-tRNA aminoacylation

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ILE A 501

Chain	Residue
A	THR247
A	THR252
A	MET336
A	HIS341
A	ASP342
A	ASP345

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site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE ILE B 601

Chain	Residue
B	ARG249
B	THR252
B	MET336
B	ASP345
A	ASP364
B	THR247
B	THR248

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