2AJ4

Crystal structure of Saccharomyces cerevisiae Galactokinase in complex with galactose and Mg:AMPPNP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0000411	biological_process	positive regulation of transcription by galactose
A	0000435	biological_process	positive regulation of transcription from RNA polymerase II promoter by galactose
A	0004335	molecular_function	galactokinase activity
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005634	cellular_component	nucleus
A	0005667	cellular_component	transcription regulator complex
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006012	biological_process	galactose metabolic process
A	0016301	molecular_function	kinase activity
A	0016740	molecular_function	transferase activity
A	0016773	molecular_function	phosphotransferase activity, alcohol group as acceptor
A	0033499	biological_process	galactose catabolic process via UDP-galactose, Leloir pathway
A	0046835	biological_process	carbohydrate phosphorylation
B	0000166	molecular_function	nucleotide binding
B	0000411	biological_process	positive regulation of transcription by galactose
B	0000435	biological_process	positive regulation of transcription from RNA polymerase II promoter by galactose
B	0004335	molecular_function	galactokinase activity
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005634	cellular_component	nucleus
B	0005667	cellular_component	transcription regulator complex
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006012	biological_process	galactose metabolic process
B	0016301	molecular_function	kinase activity
B	0016740	molecular_function	transferase activity
B	0016773	molecular_function	phosphotransferase activity, alcohol group as acceptor
B	0033499	biological_process	galactose catabolic process via UDP-galactose, Leloir pathway
B	0046835	biological_process	carbohydrate phosphorylation

Functional Information from PROSITE/UniProt

site_id	PS00106
Number of Residues	12
Details	GALACTOKINASE Galactokinase signature. GRvNLIGEHiDY

Chain	Residue	Details
A	GLY52-TYR63

---

site_id	PS00627
Number of Residues	12
Details	GHMP_KINASES_ATP GHMP kinases putative ATP-binding domain. VPtGsGLSSSAA

Chain	Residue	Details
A	VAL162-ALA173

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"UniProtKB","id":"Q9HHB6","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	28
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16115868","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2AJ4","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Site: {"description":"Transition state stabilizer","evidences":[{"source":"UniProtKB","id":"Q9HHB6","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"19779198","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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