2AG1
Crystal structure of Benzaldehyde lyase (BAL)- SeMet
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0003984 | molecular_function | acetolactate synthase activity |
| A | 0005948 | cellular_component | acetolactate synthase complex |
| A | 0009097 | biological_process | isoleucine biosynthetic process |
| A | 0009099 | biological_process | L-valine biosynthetic process |
| A | 0016829 | molecular_function | lyase activity |
| A | 0019752 | biological_process | carboxylic acid metabolic process |
| A | 0030976 | molecular_function | thiamine pyrophosphate binding |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0003984 | molecular_function | acetolactate synthase activity |
| B | 0005948 | cellular_component | acetolactate synthase complex |
| B | 0009097 | biological_process | isoleucine biosynthetic process |
| B | 0009099 | biological_process | L-valine biosynthetic process |
| B | 0016829 | molecular_function | lyase activity |
| B | 0019752 | biological_process | carboxylic acid metabolic process |
| B | 0030976 | molecular_function | thiamine pyrophosphate binding |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| C | 0000287 | molecular_function | magnesium ion binding |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0003984 | molecular_function | acetolactate synthase activity |
| C | 0005948 | cellular_component | acetolactate synthase complex |
| C | 0009097 | biological_process | isoleucine biosynthetic process |
| C | 0009099 | biological_process | L-valine biosynthetic process |
| C | 0016829 | molecular_function | lyase activity |
| C | 0019752 | biological_process | carboxylic acid metabolic process |
| C | 0030976 | molecular_function | thiamine pyrophosphate binding |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| D | 0000287 | molecular_function | magnesium ion binding |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0003984 | molecular_function | acetolactate synthase activity |
| D | 0005948 | cellular_component | acetolactate synthase complex |
| D | 0009097 | biological_process | isoleucine biosynthetic process |
| D | 0009099 | biological_process | L-valine biosynthetic process |
| D | 0016829 | molecular_function | lyase activity |
| D | 0019752 | biological_process | carboxylic acid metabolic process |
| D | 0030976 | molecular_function | thiamine pyrophosphate binding |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0050660 | molecular_function | flavin adenine dinucleotide binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 601 |
| Chain | Residue |
| A | ASP448 |
| A | ASN475 |
| A | SER477 |
| A | TPP602 |
| A | HOH5011 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG B 611 |
| Chain | Residue |
| B | TPP612 |
| B | HOH5022 |
| B | ASP448 |
| B | ASN475 |
| B | SER477 |
| B | GLY479 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG C 621 |
| Chain | Residue |
| C | ASP448 |
| C | ASN475 |
| C | SER477 |
| C | TPP622 |
| C | HOH5033 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG D 631 |
| Chain | Residue |
| D | ASP448 |
| D | ASN475 |
| D | SER477 |
| D | TPP632 |
| D | HOH5044 |
| site_id | AC5 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR RESIDUE TPP A 602 |
| Chain | Residue |
| A | GLY393 |
| A | ALA394 |
| A | LEU395 |
| A | THR396 |
| A | GLY419 |
| A | SER420 |
| A | MSE421 |
| A | GLY447 |
| A | ASP448 |
| A | GLY449 |
| A | SER450 |
| A | TYR453 |
| A | ASN475 |
| A | SER477 |
| A | TRP478 |
| A | GLY479 |
| A | ALA480 |
| A | MG601 |
| A | HOH5011 |
| B | HIS26 |
| B | GLY27 |
| B | GLU50 |
| B | THR73 |
| B | ASN80 |
| B | GLN113 |
| B | HOH5027 |
| site_id | AC6 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE TPP B 612 |
| Chain | Residue |
| A | HIS26 |
| A | GLY27 |
| A | GLU50 |
| A | THR73 |
| A | ASN80 |
| A | GLN113 |
| B | GLY393 |
| B | ALA394 |
| B | LEU395 |
| B | THR396 |
| B | GLY419 |
| B | SER420 |
| B | MSE421 |
| B | GLY447 |
| B | ASP448 |
| B | GLY449 |
| B | SER450 |
| B | TYR453 |
| B | ASN475 |
| B | SER477 |
| B | TRP478 |
| B | GLY479 |
| B | ALA480 |
| B | MG611 |
| B | HOH5022 |
| site_id | AC7 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE TPP C 622 |
| Chain | Residue |
| C | GLY393 |
| C | ALA394 |
| C | LEU395 |
| C | THR396 |
| C | GLY419 |
| C | SER420 |
| C | MSE421 |
| C | GLY447 |
| C | ASP448 |
| C | GLY449 |
| C | SER450 |
| C | TYR453 |
| C | ASN475 |
| C | SER477 |
| C | TRP478 |
| C | GLY479 |
| C | ALA480 |
| C | MG621 |
| C | HOH5033 |
| D | HIS26 |
| D | GLU50 |
| D | THR73 |
| D | GLY76 |
| D | ASN80 |
| D | GLN113 |
| site_id | AC8 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE TPP D 632 |
| Chain | Residue |
| C | GLU50 |
| C | ASN80 |
| C | GLN113 |
| D | GLY393 |
| D | ALA394 |
| D | LEU395 |
| D | THR396 |
| D | GLY419 |
| D | SER420 |
| D | MSE421 |
| D | GLY447 |
| D | ASP448 |
| D | GLY449 |
| D | SER450 |
| D | TYR453 |
| D | ASN475 |
| D | SER477 |
| D | TRP478 |
| D | GLY479 |
| D | ALA480 |
| D | MG631 |
| D | HOH5044 |
| C | HIS26 |
| C | GLY27 |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 4 |
| Details | M-CSA 221 |
| Chain | Residue | Details |
| A | CYS37 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| A | GLU58 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| A | MSE121 | electrostatic stabiliser, hydrogen bond acceptor |
| A | ASP459 | electrostatic stabiliser, hydrogen bond acceptor |
| site_id | MCSA2 |
| Number of Residues | 4 |
| Details | M-CSA 221 |
| Chain | Residue | Details |
| B | CYS37 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| B | GLU58 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| B | MSE121 | electrostatic stabiliser, hydrogen bond acceptor |
| B | ASP459 | electrostatic stabiliser, hydrogen bond acceptor |
| site_id | MCSA3 |
| Number of Residues | 4 |
| Details | M-CSA 221 |
| Chain | Residue | Details |
| C | CYS37 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| C | GLU58 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| C | MSE121 | electrostatic stabiliser, hydrogen bond acceptor |
| C | ASP459 | electrostatic stabiliser, hydrogen bond acceptor |
| site_id | MCSA4 |
| Number of Residues | 4 |
| Details | M-CSA 221 |
| Chain | Residue | Details |
| D | CYS37 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| D | GLU58 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| D | MSE121 | electrostatic stabiliser, hydrogen bond acceptor |
| D | ASP459 | electrostatic stabiliser, hydrogen bond acceptor |
