2AFA

Crystal Structure of putative NAG isomerase from Salmonella typhimurium

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005975	biological_process	carbohydrate metabolic process
A	0016853	molecular_function	isomerase activity
A	0061593	molecular_function	sulfoquinovose isomerase activity
A	0061720	biological_process	6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde
A	1902777	biological_process	6-sulfoquinovose(1-) catabolic process
B	0005975	biological_process	carbohydrate metabolic process
B	0016853	molecular_function	isomerase activity
B	0061593	molecular_function	sulfoquinovose isomerase activity
B	0061720	biological_process	6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde
B	1902777	biological_process	6-sulfoquinovose(1-) catabolic process
C	0005975	biological_process	carbohydrate metabolic process
C	0016853	molecular_function	isomerase activity
C	0061593	molecular_function	sulfoquinovose isomerase activity
C	0061720	biological_process	6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde
C	1902777	biological_process	6-sulfoquinovose(1-) catabolic process
D	0005975	biological_process	carbohydrate metabolic process
D	0016853	molecular_function	isomerase activity
D	0061593	molecular_function	sulfoquinovose isomerase activity
D	0061720	biological_process	6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde
D	1902777	biological_process	6-sulfoquinovose(1-) catabolic process
E	0005975	biological_process	carbohydrate metabolic process
E	0016853	molecular_function	isomerase activity
E	0061593	molecular_function	sulfoquinovose isomerase activity
E	0061720	biological_process	6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde
E	1902777	biological_process	6-sulfoquinovose(1-) catabolic process
F	0005975	biological_process	carbohydrate metabolic process
F	0016853	molecular_function	isomerase activity
F	0061593	molecular_function	sulfoquinovose isomerase activity
F	0061720	biological_process	6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde
F	1902777	biological_process	6-sulfoquinovose(1-) catabolic process

Functional Information from PROSITE/UniProt

site_id	PS01295
Number of Residues	8
Details	ISPD 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. VIIHDVAR

Chain	Residue	Details
A	VAL205-ARG212

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	ACT_SITE: Proton donor/acceptor => ECO:0000255|HAMAP-Rule:MF_00998, ECO:0000305|PubMed:18328504, ECO:0000305|PubMed:33791429

Chain	Residue	Details
A	HIS250
E	HIS386
F	HIS250
F	HIS386
A	HIS386
B	HIS250
B	HIS386
C	HIS250
C	HIS386
D	HIS250
D	HIS386
E	HIS250

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site_id	SWS_FT_FI2
Number of Residues	36
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00998, ECO:0000305|PubMed:18328504, ECO:0000305|PubMed:33791429, ECO:0007744|PDB:7AG4

Chain	Residue	Details
A	ARG57
B	HIS178
B	ARG240
B	GLU253
C	ARG57
C	TYR113
C	ASN174
C	HIS178
C	ARG240
C	GLU253
D	ARG57
A	TYR113
D	TYR113
D	ASN174
D	HIS178
D	ARG240
D	GLU253
E	ARG57
E	TYR113
E	ASN174
E	HIS178
E	ARG240
A	ASN174
E	GLU253
F	ARG57
F	TYR113
F	ASN174
F	HIS178
F	ARG240
F	GLU253
A	HIS178
A	ARG240
A	GLU253
B	ARG57
B	TYR113
B	ASN174

---

site_id	SWS_FT_FI3
Number of Residues	18
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00998, ECO:0000305|PubMed:33791429, ECO:0007744|PDB:7AG4

Chain	Residue	Details
A	GLN365
D	GLN365
D	GLN382
D	HIS386
E	GLN365
E	GLN382
E	HIS386
F	GLN365
F	GLN382
F	HIS386
A	GLN382
A	HIS386
B	GLN365
B	GLN382
B	HIS386
C	GLN365
C	GLN382
C	HIS386

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