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2AEQ

An epidemiologically significant epitope of a 1998 influenza virus neuraminidase forms a highly hydrated interface in the NA-antibody complex.

Functional Information from GO Data
ChainGOidnamespacecontents
A0004308molecular_functionexo-alpha-sialidase activity
A0005975biological_processcarbohydrate metabolic process
A0016020cellular_componentmembrane
A0033644cellular_componenthost cell membrane
A0046761biological_processviral budding from plasma membrane
A0055036cellular_componentvirion membrane
H0002250biological_processadaptive immune response
H0002376biological_processimmune system process
H0003823molecular_functionantigen binding
H0005576cellular_componentextracellular region
H0016064biological_processimmunoglobulin mediated immune response
H0019814cellular_componentimmunoglobulin complex
Functional Information from PROSITE/UniProt
site_idPS00022
Number of Residues12
DetailsEGF_1 EGF-like domain signature 1. CsCypRypGVrC
ChainResidueDetails
ACYS278-CYS289

site_idPS00290
Number of Residues7
DetailsIG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH
ChainResidueDetails
LTYR192-HIS198

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI6
Number of Residues4
DetailsRegion: {"description":"D segment","evidences":[{"source":"UniProtKB","id":"P01783","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

Catalytic Information from CSA
site_idCSA1
Number of Residues2
DetailsAnnotated By Reference To The Literature 1a4g
ChainResidueDetails
AASP151
AGLU277

246031

PDB entries from 2025-12-10

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