2A8A
Crystal structure of Clostridium botulinum neurotoxin serotype F light chain
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN A 440 |
| Chain | Residue |
| A | HIS227 |
| A | HIS231 |
| A | GLU266 |
| A | HOH523 |
| A | HOH541 |
| A | HOH551 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CD A 441 |
| Chain | Residue |
| A | ASP383 |
| A | ASP383 |
| A | HOH605 |
| A | HOH605 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CD A 442 |
| Chain | Residue |
| A | HIS122 |
| A | GLU246 |
| A | HOH494 |
| A | HOH608 |
| site_id | CDA |
| Number of Residues | 2 |
| Details | FIRST CADMIUM BINDING SITE |
| Chain | Residue |
| A | ASP383 |
| A | HOH605 |
| site_id | CDB |
| Number of Residues | 3 |
| Details | SECOND CADMIUM BINDING SITE |
| Chain | Residue |
| A | HOH608 |
| A | HOH494 |
| A | GLU246 |
| site_id | ZNB |
| Number of Residues | 6 |
| Details | ZINC BINDING SITE |
| Chain | Residue |
| A | HIS227 |
| A | HIS231 |
| A | GLU266 |
| A | HOH523 |
| A | HOH541 |
| A | HOH551 |
Functional Information from PROSITE/UniProt
| site_id | PS00142 |
| Number of Residues | 10 |
| Details | ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. SLAHELIHAL |
| Chain | Residue | Details |
| A | SER224-LEU233 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10095","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10095","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"16128577","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2A8A","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2A97","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16128577","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2A8A","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2A97","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1i1e |
| Chain | Residue | Details |
| A | TYR368 | |
| A | GLU266 | |
| A | ARG365 |
