2A7S

Crystal Structure of the Acyl-CoA Carboxylase, AccD5, from Mycobacterium tuberculosis

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003989	molecular_function	acetyl-CoA carboxylase activity
A	0004658	molecular_function	propionyl-CoA carboxylase activity
A	0005515	molecular_function	protein binding
A	0005886	cellular_component	plasma membrane
A	0006629	biological_process	lipid metabolic process
A	0009274	cellular_component	peptidoglycan-based cell wall
A	0009317	cellular_component	acetyl-CoA carboxylase complex
A	0015977	biological_process	carbon fixation
A	0016740	molecular_function	transferase activity
A	0016874	molecular_function	ligase activity
A	0032991	cellular_component	protein-containing complex
A	0042802	molecular_function	identical protein binding
B	0003989	molecular_function	acetyl-CoA carboxylase activity
B	0004658	molecular_function	propionyl-CoA carboxylase activity
B	0005515	molecular_function	protein binding
B	0005886	cellular_component	plasma membrane
B	0006629	biological_process	lipid metabolic process
B	0009274	cellular_component	peptidoglycan-based cell wall
B	0009317	cellular_component	acetyl-CoA carboxylase complex
B	0015977	biological_process	carbon fixation
B	0016740	molecular_function	transferase activity
B	0016874	molecular_function	ligase activity
B	0032991	cellular_component	protein-containing complex
B	0042802	molecular_function	identical protein binding
C	0003989	molecular_function	acetyl-CoA carboxylase activity
C	0004658	molecular_function	propionyl-CoA carboxylase activity
C	0005515	molecular_function	protein binding
C	0005886	cellular_component	plasma membrane
C	0006629	biological_process	lipid metabolic process
C	0009274	cellular_component	peptidoglycan-based cell wall
C	0009317	cellular_component	acetyl-CoA carboxylase complex
C	0015977	biological_process	carbon fixation
C	0016740	molecular_function	transferase activity
C	0016874	molecular_function	ligase activity
C	0032991	cellular_component	protein-containing complex
C	0042802	molecular_function	identical protein binding
D	0003989	molecular_function	acetyl-CoA carboxylase activity
D	0004658	molecular_function	propionyl-CoA carboxylase activity
D	0005515	molecular_function	protein binding
D	0005886	cellular_component	plasma membrane
D	0006629	biological_process	lipid metabolic process
D	0009274	cellular_component	peptidoglycan-based cell wall
D	0009317	cellular_component	acetyl-CoA carboxylase complex
D	0015977	biological_process	carbon fixation
D	0016740	molecular_function	transferase activity
D	0016874	molecular_function	ligase activity
D	0032991	cellular_component	protein-containing complex
D	0042802	molecular_function	identical protein binding
E	0003989	molecular_function	acetyl-CoA carboxylase activity
E	0004658	molecular_function	propionyl-CoA carboxylase activity
E	0005515	molecular_function	protein binding
E	0005886	cellular_component	plasma membrane
E	0006629	biological_process	lipid metabolic process
E	0009274	cellular_component	peptidoglycan-based cell wall
E	0009317	cellular_component	acetyl-CoA carboxylase complex
E	0015977	biological_process	carbon fixation
E	0016740	molecular_function	transferase activity
E	0016874	molecular_function	ligase activity
E	0032991	cellular_component	protein-containing complex
E	0042802	molecular_function	identical protein binding
F	0003989	molecular_function	acetyl-CoA carboxylase activity
F	0004658	molecular_function	propionyl-CoA carboxylase activity
F	0005515	molecular_function	protein binding
F	0005886	cellular_component	plasma membrane
F	0006629	biological_process	lipid metabolic process
F	0009274	cellular_component	peptidoglycan-based cell wall
F	0009317	cellular_component	acetyl-CoA carboxylase complex
F	0015977	biological_process	carbon fixation
F	0016740	molecular_function	transferase activity
F	0016874	molecular_function	ligase activity
F	0032991	cellular_component	protein-containing complex
F	0042802	molecular_function	identical protein binding

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1536
Details	Domain: {"description":"CoA carboxyltransferase N-terminal","evidences":[{"source":"PROSITE-ProRule","id":"PRU01136","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1476
Details	Domain: {"description":"CoA carboxyltransferase C-terminal","evidences":[{"source":"PROSITE-ProRule","id":"PRU01137","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	4
Details	Annotated By Reference To The Literature 1xny

Chain	Residue	Details
A	ALA435
A	GLY434
D	GLY193
D	GLY194

---

site_id	CSA2
Number of Residues	4
Details	Annotated By Reference To The Literature 1xny

Chain	Residue	Details
E	GLY193
E	GLY194
B	ALA435
B	GLY434

---

site_id	CSA3
Number of Residues	4
Details	Annotated By Reference To The Literature 1xny

Chain	Residue	Details
F	GLY193
F	GLY194
C	ALA435
C	GLY434

---

site_id	CSA4
Number of Residues	4
Details	Annotated By Reference To The Literature 1xny

Chain	Residue	Details
A	GLY193
A	GLY194
D	ALA435
D	GLY434

---

site_id	CSA5
Number of Residues	4
Details	Annotated By Reference To The Literature 1xny

Chain	Residue	Details
E	ALA435
E	GLY434
B	GLY193
B	GLY194

---

site_id	CSA6
Number of Residues	4
Details	Annotated By Reference To The Literature 1xny

Chain	Residue	Details
F	ALA435
F	GLY434
C	GLY193
C	GLY194

---